Myelin water imaging (MWI) is an MRI imaging biomarker for myelin. This method can
generate an in vivo whole‐brain myelin water fraction map in approximately 10 minutes. It …

Rapid and efficient transmission of electric signals among neurons of vertebrates is ensured
by myelin‐insulating sheaths surrounding axons. Human cognition, sensation, and motor …

Background The g-ratio, quantifying the comparative thickness of the myelin sheath
encasing an axon, is a geometrical invariant that has high functional relevance because of …

Purpose To enhance the visibility of nigrosome 1 in substantia nigra, which has recently
been suggested as an imaging biomarker for Parkinson's disease (PD) at 3T magnetic …

A number of central nervous system (CNS) diseases exhibit changes in myelin content and
magnetic resonance longitudinal, T 1, and transverse, T 2, relaxation times, which therefore …

Myelin water imaging techniques based on multi-compartment relaxometry have been
developed as an important tool to measure myelin concentration in vivo, but are limited by …

In MRI, structurally aligned molecular or micro‐organization (eg axonal fibers) can be a
source of substantial signal variations that depend on the structural orientation and the …

MR g-ratio, which measures the ratio of the aggregate volume of axons to that of fibers in a
voxel, is a potential biomarker for white matter microstructures. In this study, a new approach …

Magnetic resonance imaging (MRI) of focal or diffuse myelin damage or remyelination may
provide important insights into disease progression and potential treatment efficacy in …

The choice of a pulse sequence at ultra-high field can be influenced by a number of
considerations and constraints that are not always the same as those at lower fields …