Red blood cell transfusions have reduced morbidity and mortality for patients with sickle cell
disease. Transfusions can lead to erythrocyte alloimmunization, however, with serious …

The acute blood transfusion reactions are responsible for causing most serious adverse
events. Awareness about various clinical features of acute and delayed transfusion …

Red blood cell (RBC) transfusions can be life‐sustaining in chronic inherited anaemias,
such as thalassaemia, and the indications for blood transfusions in patients with sickle cell …

Red blood cell (RBC) transfusion is unique as a common large-scale intravenous
introduction of foreign tissue and provides a valuable opportunity to study human …

Red blood cell (RBC) transfusions are a milestone in the treatment for sickle cell anaemia
(SSA) and for thalassaemia. RBC alloimmunization remains a major challenge of chronic …

BACKGROUND: Blood transfusion is an integral part in the management of sickle cell
disease (SCD) patients. Alloimmunization is a recognized complication of red blood cell …

Transfusion therapy is effective in the prevention and treatment of many complications of
sickle cell disease (SCD). However, its benefits must be balanced against its risks, including …

The development of hemolytic erythrocyte alloantibodies and autoantibodies complicates
transfusion therapy in thalassemia patients. These antibodies ultimately increase the need …

Background Patients with malignancy comprise a unique group for whom transfusions play
an important role. Because the need for transfusions may span a long period of time, these …

Blood group antigens, present on the cell membrane of red blood cells and platelets, can be
defined either serologically or predicted based on the genotypes of genes encoding for …