Knowing the beneficial aspects of nanomedicine, scientists are trying to harness the
applications of nanotechnology in diagnosis, treatment, and prevention of diseases. There …

The large incidence of bone defects in clinical practice increases not only the demand for
advanced bone transplantation techniques but also the development of bone substitute …

Aim Human stem cells from the apical papilla (SCAPs) are an appealing stem cell source for
tissue regeneration engineering. Circular RNAs (circRNAs) are known to exert pivotal …

In recent decades, human mesenchymal stem cells (hMSCs) have gained momentum in the
field of cell therapy for treating cartilage and bone injuries. Despite the tri-lineage …

Physical factors in the cellular microenvironment have critical effects on stem cell
differentiation. The utilization of physical factors to promote the osteogenic differentiation of …

MicroRNAs (miRNAs) play a pivotal role in regulating gene expression and are considered
new molecular targets in bone tissue engineering. However, effective delivery of miRNAs to …

In addition to transmitting and carrying genetic information, RNA plays an important abiotic
role in the world of nanomaterials. RNA is a natural polyanionic biomacromolecule, and its …

Drug delivery methods utilizing nanomaterials show potential for personalized medicine
strategies, enabling customized treatments that take into account certain patient attributes …

1. Chen LL, Song JX, Lu JH, Yuan ZW, Liu LF, Durairajan SSK, Li M.*(2014)“Corynoxine, a
natural mTOR inhibitor, promotes the clearance of alpha-synuclein by inducing autophagy” …