Improving the efficacy of anti-EGFR drugs in GBM: Where we are going?

M Ge, Y Zhu, M Wei, H Piao, M He - … et Biophysica Acta (BBA)-Reviews on …, 2023 - Elsevier
The therapies targeting mutations of driver genes in cancer have advanced into clinical trials
for a variety of tumors. In glioblastoma (GBM), epidermal growth factor receptor (EGFR) is …

Artificial intelligence in digital histopathology for predicting patient prognosis and treatment efficacy in breast cancer

C McCaffrey, C Jahangir, C Murphy… - Expert Review of …, 2024 - Taylor & Francis
Introduction Histological images contain phenotypic information predictive of patient
outcomes. Due to the heavy workload of pathologists, the time-consuming nature of …

[HTML][HTML] Analytical validation of the PreciseDx digital prognostic breast cancer test in early-stage breast cancer

G Fernandez, J Zeineh, M Prastawa, R Scott… - Clinical Breast …, 2024 - Elsevier
Abstract Background: PreciseDx Breast is a digital test that predicts early-stage breast
cancer recurrence within 6-years of diagnosis. Materials and Methods: Using hematoxylin …

Current controversies in the use of Oncotype DX in early breast cancer

PPMB Giachetti, AC Schianca, D Trapani… - Cancer Treatment …, 2025 - Elsevier
Multigene prognostic genomic assays have become essential tools in the management of
early breast cancer (BC), providing information that help in risk-stratification, to provide risk …

Deep learning-based risk stratification of preoperative breast biopsies using digital whole slide images

C Boissin, Y Wang, A Sharma, P Weitz… - Breast Cancer …, 2024 - Springer
Background Nottingham histological grade (NHG) is a well established prognostic factor in
breast cancer histopathology but has a high inter-assessor variability with many tumours …

The yin and yang of chromosomal instability in prostate cancer

M Carceles-Cordon, JJ Orme… - Nature Reviews …, 2024 - nature.com
Metastatic prostate cancer remains an incurable lethal disease. Studies indicate that
prostate cancer accumulates genomic changes during disease progression and displays the …

Automated Prognosis Marker Assessment in Breast Cancers Using BLEACH&STAIN Multiplexed Immunohistochemistry

T Mandelkow, E Bady, MCJ Lurati, JB Raedler… - Biomedicines, 2023 - mdpi.com
Prognostic markers in routine clinical management of breast cancer are often assessed
using RNA-based multi-gene panels that depend on fluctuating tumor purity. Multiplex …

US payer budget impact of using an AI-augmented cancer risk discrimination digital histopathology platform to identify high-risk of recurrence in women with early …

SF Masud, N Mark, T Goss, D Malinowski… - Journal of Medical …, 2024 - Taylor & Francis
Aims Use of gene expression signatures to predict adjuvant chemotherapy benefit in women
with early-stage breast cancer is increasing. However, high cost, limited access, and …

Construction and validation of a nomogram for predicting the prognosis of patients with lymph node-positive invasive micropapillary carcinoma of the breast: based on …

Y Li, J Liu, Z Xu, J Shang, S Wu, M Zhang… - Frontiers in …, 2023 - frontiersin.org
Background Invasive micropapillary carcinoma (IMPC) of the breast is a rare subtype of
breast cancer with high incidence of aggressive clinical behavior, lymph node metastasis …

Breast Cancer Image Classification Obtained Through Dynamic Thermography using Deep Learning

ED Timadius, R Wongso, T Baihaqi… - … of Science and …, 2024 - ieeexplore.ieee.org
This paper addresses the vital task of diagnosing breast cancer early and accurately. It
acknowledges the difficulty in detecting minor variations in breast cancer patterns through …