Alpha-lipoic acid (ALA) is a natural compound with antioxidant and pro-oxidant properties
which has effects on the regulation of insulin sensitivity and insulin secretion. ALA is widely …

Oxidative stress is generated by the imbalance between reactive oxygen species (ROS)
formation and antioxidant scavenger system's activity. Increased ROS, such as superoxide …

Precise and controlled drug delivery to treat periodontitis in patients with diabetes remains a
significant clinical challenge. Nanoparticle-based drug delivery systems offer a potential …

Diabetic kidney disease (DKD) has become the leading cause of end-stage renal disease
(ESRD), and the prevalence of DKD has increased worldwide during recent years. DKD is …

Alpha-lipoic acid (ALA) is a natural short-chain fatty acid that has attracted great attention in
recent years as an antioxidant molecule. However, some concerns have been recently …

Increased life expectancy, attributed to improved access to healthcare and drug
development, has led to an increase in multimorbidity, a key contributor to polypharmacy …

Pathological deterioration of mitochondrial function is increasingly linked with multiple
degenerative illnesses as a mediator of a wide range of neurologic and age-related chronic …

Diabetes-associated cognitive impairment (DACI) is a common complication of diabetes
mellitus (DM) that affects the central nervous system. Cognitive impairment, such as learning …

The development of painful diabetic neuropathy (PDN) is a common complication of chronic
diabetes that can be associated with significant disability and healthcare costs. Prompt …

Background There are numerous trials reported the effect of alpha‐lipoic acid (ALA) on
obesity measurements; while no summarised dose‐response meta‐analysis is available to …