Aims Hypertension is one of the major causes of cardiac damage. In this study, the effects of
resveratrol supplementation and regular exercise on hypertension-induced cellular stress …

The heart is the first organ to acquire its physiological function during development, enabling
it to supply the organism with oxygen and nutrients. Given this early commitment …

We conducted a clinical trial with 22 healthy volunteers to investigate the effects of pregnane
X receptor (PXR) agonist rifampin on blood pressure (BP). The study was randomized …

Background Mechanisms mediating hypertensive effects of overweight and obesity have not
been fully elucidated. We showed previously that activation of pregnane X receptor (PXR) by …

Background: The genetic factors in assessing therapeutic efficacy and predicting
antihypertensive drug response are unclear. Therefore, this study aims to identify the …

Deoxycorticosterone (DOC) was the first steroid with significant mineralocorticoid action to
be discovered. It was synthesized more than a decade before the more potent primary …

Hypertension is a common disease that affects many organs including heart, vessel, and
kidney. Moreover, chronic hypertension can lead to hepatic impairments accompanied by …

Karaciğer X reseptörleri (LXR), hücre çekirdeğinde bulunan ve “çekirdek reseptörleri” olarak
sınıflandırılan reseptörlerdir. Bu reseptörlerin LXR alfa ve LXR beta olmak üzere iki alt tipi …