Neonatal sepsis definitions from randomised clinical trials

R Hayes, J Hartnett, G Semova, C Murray, K Murphy… - Pediatric …, 2023 - nature.com
Introduction Neonatal sepsis is a leading cause of infant mortality worldwide with non-
specific and varied presentation. We aimed to catalogue the current definitions of neonatal …

Vital signs as physiomarkers of neonatal sepsis

BA Sullivan, KD Fairchild - Pediatric research, 2022 - nature.com
Neonatal sepsis accounts for significant morbidity and mortality, particularly among
premature infants in the Neonatal Intensive Care Unit. Abnormal vital sign patterns serve as …

Updates in late-onset sepsis: risk assessment, therapy, and outcomes

SA Coggins, K Glaser - Neoreviews, 2022 - publications.aap.org
Neonatal late-onset sepsis (LOS) continues to threaten morbidity and mortality in the NICU
and poses ongoing diagnostic and therapeutic challenges. Early recognition of clinical …

Improving child health through Big Data and data science

ZA Vesoulis, AN Husain, FS Cole - Pediatric research, 2023 - nature.com
Child health is defined by a complex, dynamic network of genetic, cultural, nutritional,
infectious, and environmental determinants at distinct, developmentally determined epochs …

Development and validation of a sepsis diagnostic scoring model for neonates with suspected sepsis

R Sokou, G Ioakeimidis, D Piovani… - Frontiers in …, 2022 - frontiersin.org
Background We aimed to develop and validate a diagnostic model for sepsis among
neonates evaluated for suspected sepsis, by incorporating thromboelastometry parameters …

Data-driven longitudinal characterization of neonatal health and morbidity

D De Francesco, JD Reiss, J Roger, AS Tang… - Science translational …, 2023 - science.org
Although prematurity is the single largest cause of death in children under 5 years of age,
the current definition of prematurity, based on gestational age, lacks the precision needed …

Assessment of hemostatic profile in neonates with necrotizing enterocolitis using rotational thromboelastometry (ROTEM)

R Sokou, P Mantzios, AG Tsantes, S Parastatidou… - Pediatric …, 2024 - nature.com
Background This study aimed to explore the hemostatic profile of neonates with necrotizing
enterocolitis (NEC) using Rotational Thromboelastometry (ROTEM) and to investigate if …

[PDF][PDF] A proposed framework for the clinical management of neonatal “culture-negative” sepsis

JB Cantey, P Prusakov - The Journal of Pediatrics, 2022 - Elsevier
Conclusions It is impossible to say with certainty that “culture-negative” sepsis does not
exist. Myriad observational data support the experience of an infant with clinical signs of …

Prevalence of multidrug-resistant pathogens causing neonatal early and late onset sepsis, a retrospective study from the tertiary referral children's hospital

P Fang, K Gao, J Yang, T Li, W Gong… - Infection and Drug …, 2023 - Taylor & Francis
Introduction Sepsis is the most severe infectious disease with the highest mortality rate,
particularly among neonates admitted to the neonatal intensive care unit (NICU). This study …

Evaluation of the neonatal sequential organ failure assessment and mortality risk in preterm infants with necrotizing enterocolitis

AN Lewis, D de la Cruz, JL Wynn, LC Frazer, W Yakah… - Neonatology, 2022 - karger.com
Introduction: The neonatal sequential organ failure assessment (nSOFA) score is a tool for
calculating mortality risk of infants in the neonatal intensive care unit. The utility of the …