[HTML][HTML] OxInflammatory responses in the wound healing process: a systematic review

FB Lopes, MM Sarandy, RD Novaes, G Valacchi… - Antioxidants, 2024 - mdpi.com
Significant sums are spent every year to find effective treatments to control inflammation and
speed up the repair of damaged skin. This study investigated the main mechanisms involved …

Roles of miRNAs in regulating ovarian cancer stemness

C Zhi-Xiong - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2024 - Elsevier
Ovarian cancer is one of the gynaecology malignancies with the highest mortality rate.
Ovarian cancer stem cell (CSC) is a subpopulation of ovarian cancer cells with increased …

Modulation of kinase activities in vitro by hepatitis C virus protease NS3/NS4A mediated-cleavage of key immune modulator kinases

MAF Abdullah, SM McWhirter, Z Suo - Cells, 2023 - mdpi.com
Hepatitis C Virus NS3/NS4A, a serine protease complex, has been found to interact with
many host proteins and cause various adverse effects on cellular function and immune …

The host antiviral protein SAMHD1 suppresses NF-κB activation by interacting with the IKK complex during inflammatory responses and viral infection

H Yang, CE Espada, S Phillips, N Martinez… - Journal of Biological …, 2023 - ASBMB
Sterile alpha motif and histidine-aspartate (HD) domain–containing protein 1 (SAMHD1)
inhibits HIV-1 replication in nondividing cells by reducing the intracellular dNTP pool …

Dragon's blood attenuates LPS-induced intestinal epithelial barrier dysfunction via upregulation of FAK-DOCK180-Rac1-WAVE2-Arp3 and downregulation of TLR4 …

H Liu, R Yan, Y Li, J Wang, Y Deng, Y Li - Journal of Natural Medicines, 2024 - Springer
Inflammation-induced intestinal epithelial barrier (IEB) dysfunction is one of the important
reasons for the occurrence and development of intestinal inflammatory-related diseases …

TRPV4 in adipose tissue ameliorates diet-induced obesity by promoting white adipocyte browning

Y Zhang, J Xue, W Zhu, H Wang, P Xi, D Tian - Translational Research, 2024 - Elsevier
The induction of adipocyte browning to increase energy expenditure is a promising strategy
to combat obesity. Transient receptor potential channel V4 (TRPV4) functions as a …

Salvimulticanol from Salvia multicaulis suppresses LPS-induced inflammation in RAW264.7 macrophages: in vitro and in silico studies

AR Hamed, HK Nabih, AA El-Rashedy, TA Mohamed… - 3 Biotech, 2024 - Springer
Sustained inflammatory responses can badly affect several vital organs and lead to chronic
inflammation-related disorders, such as atherosclerosis, pneumonia, rheumatoid arthritis …

Dual-specific autophosphorylation of kinase IKK2 enables phosphorylation of substrate IκBα through a phosphoenzyme intermediate

P Borar, T Biswas, A Chaudhuri, T Pallavi Rao… - bioRxiv, 2023 - biorxiv.org
IKK2, a Ser/Thr kinase, acts as a gateway to canonical activation of NF-κB underlying stress
signalling. The immediate targets of IKK2 are two serines (S32 and S36) of IκBα, which …