Measuring DNA modifications with the comet assay: a compendium of protocols

A Collins, P Møller, G Gajski, S Vodenková… - Nature protocols, 2023 - nature.com
The comet assay is a versatile method to detect nuclear DNA damage in individual
eukaryotic cells, from yeast to human. The types of damage detected encompass DNA …

[HTML][HTML] A weight of evidence review of the genotoxicity of titanium dioxide (TiO2)

D Kirkland, MJ Aardema, RV Battersby… - Regulatory Toxicology …, 2022 - Elsevier
Titanium dioxide is a ubiquitous white material found in a diverse range of products from
foods to sunscreens, as a pigment and thickener, amongst other uses. Titanium dioxide has …

Guidance on risk assessment of nanomaterials to be applied in the food and feed chain: Human and animal health

EFSA Scientific Committee, S More, V Bampidis… - Efsa …, 2021 - Wiley Online Library
The EFSA has updated the Guidance on risk assessment of the application of nanoscience
and nanotechnologies in the food and feed chain, human and animal health. It covers the …

Guidance on risk assessment of nanomaterials to be applied in the food and feed chain: human and animal health

EFSA Scientific Committee - EFSA Journal, 2021 - orbit.dtu.dk
The EFSA has updated the Guidance on risk assessment of the application of nanoscience
and nanotechnologies in the food and feed chain, human and animal health. It covers the …

Safety assessment of titanium dioxide (E171) as a food additive

EFSA Panel on Food Additives and Flavourings … - Efsa …, 2021 - Wiley Online Library
The present opinion deals with an updated safety assessment of the food additive titanium
dioxide (E 171) based on new relevant scientific evidence considered by the Panel to be …

Guidance on risk assessment of the application of nanoscience and nanotechnologies in the food and feed chain: Part 1, human and animal health

EFSA Scientific Committee, A Hardy, D Benford… - EFSA …, 2018 - Wiley Online Library
Abstract The European Food Safety Authority has produced this Guidance on human and
animal health aspects (Part 1) of the risk assessment of nanoscience and nanotechnology …

Review of key factors controlling engineered nanoparticle transport in porous media

M Wang, B Gao, D Tang - Journal of hazardous materials, 2016 - Elsevier
Nanotechnology, an emerging technology, has witnessed rapid development in production
and application. Engineered nanomaterials revolutionize the industry due to their unique …

High throughput toxicity screening and intracellular detection of nanomaterials

AR Collins, B Annangi, L Rubio… - Wiley …, 2017 - Wiley Online Library
With the growing numbers of nanomaterials (NMs), there is a great demand for rapid and
reliable ways of testing NM safety—preferably using in vitro approaches, to avoid the ethical …

[HTML][HTML] Immunotoxicity, genotoxicity and epigenetic toxicity of nanomaterials: New strategies for toxicity testing?

M Dusinska, J Tulinska, N El Yamani… - Food and Chemical …, 2017 - Elsevier
The unique properties of nanomaterials (NMs) are beneficial in numerous industrial and
medical applications. However, they could also induce unintended effects. Thus, a proper …

Hepato (geno) toxicity assessment of nanoparticles in a HepG2 liver spheroid model

E Elje, E Mariussen, OH Moriones, NG Bastús… - Nanomaterials, 2020 - mdpi.com
(1) In compliance with the 3Rs policy to reduce, refine and replace animal experiments, the
development of advanced in vitro models is needed for nanotoxicity assessment. Cells …