Impact of lipids on insulin resistance: insights from human and animal studies
Insulin resistance (IR) is a complex pathological condition central to metabolic diseases
such as type 2 diabetes mellitus (T2DM), cardiovascular disease, non-alcoholic fatty liver …
such as type 2 diabetes mellitus (T2DM), cardiovascular disease, non-alcoholic fatty liver …
Recent advances in the treatment of insulin resistance targeting molecular and metabolic pathways: fighting a losing battle?
M Wolosowicz, S Prokopiuk, TW Kaminski - Medicina, 2022 - mdpi.com
Diabetes Mellitus (DM) is amongst the most notable causes of years of life lost worldwide
and its prevalence increases perpetually. The disease is characterized as multisystemic …
and its prevalence increases perpetually. The disease is characterized as multisystemic …
[HTML][HTML] Application of P7C3 compounds to investigating and treating acute and chronic traumatic brain injury
PS Sridharan, E Miller, AA Pieper - Neurotherapeutics, 2023 - Elsevier
Traumatic brain injury (TBI) is a leading worldwide cause of disability, and there are
currently no medicines that prevent, reduce, or reverse acute or chronic neurodegeneration …
currently no medicines that prevent, reduce, or reverse acute or chronic neurodegeneration …
NAD+ centric mechanisms and molecular determinants of skeletal muscle disease and aging
S Wagner, R Manickam, M Brotto… - Molecular and cellular …, 2022 - Springer
The nicotinamide adenine dinucleotide (NAD+) is an essential redox cofactor, involved in
various physiological and molecular processes, including energy metabolism, epigenetics …
various physiological and molecular processes, including energy metabolism, epigenetics …
Dulaglutide protects mice against diabetic sarcopenia‐mediated muscle injury by inhibiting inflammation and regulating the differentiation of Myoblasts
F Deng, W Wu, X Fan, X Zhong, N Wang… - International Journal …, 2023 - Wiley Online Library
Background. Type 2 diabetes mellitus increases the risk of sarcopenia, which is
characterized by decreased muscle mass, strength, and function. However, there are no …
characterized by decreased muscle mass, strength, and function. However, there are no …
Mechanisms of the NAD+ salvage pathway in enhancing skeletal muscle function
M Su, F Qiu, Y Li, T Che, N Li, S Zhang - Frontiers in Cell and …, 2024 - frontiersin.org
Nicotinamide adenine dinucleotide (NAD+) is crucial for cellular energy production, serving
as a coenzyme in oxidation-reduction reactions. It also supports enzymes involved in …
as a coenzyme in oxidation-reduction reactions. It also supports enzymes involved in …
Channeling Nicotinamide Phosphoribosyltransferase (NAMPT) to Address Life and Death
Nicotinamide phosphoribosyltransferase (NAMPT) catalyzes the rate-limiting step in NAD+
biosynthesis via salvage of NAM formed from catabolism of NAD+ by proteins with NADase …
biosynthesis via salvage of NAM formed from catabolism of NAD+ by proteins with NADase …
[HTML][HTML] F-box only protein 2 exacerbates non-alcoholic fatty liver disease by targeting the hydroxyl CoA dehydrogenase alpha subunit
Z Liu, NY Chen, Z Zhang, S Zhou… - World Journal of …, 2023 - ncbi.nlm.nih.gov
F-box only protein 2 exacerbates non-alcoholic fatty liver disease by targeting the hydroxyl
CoA dehydrogenase alpha subunit - PMC Back to Top Skip to main content NIH NLM Logo …
CoA dehydrogenase alpha subunit - PMC Back to Top Skip to main content NIH NLM Logo …
Poor vitamin D status was associated with increased appendicular fat deposition in US Adults: Data from 2011–2018 National Health and Nutrition Examination …
Q Ren, D Xu, J Liang, Y Cao, L Zhang, S Ge, P Chen - Nutrition Research, 2024 - Elsevier
The aim of the study was to explore the relationship between serum 25-hydroxyvitamin D [25
(OH) D] concentrations and regional body fat deposition in 2011–2018 National Health and …
(OH) D] concentrations and regional body fat deposition in 2011–2018 National Health and …
NAD metabolism and heart failure: Mechanisms and therapeutic potentials
MA Walker, R Tian - Journal of Molecular and Cellular Cardiology, 2024 - Elsevier
Nicotinamide adenine dinucleotide provides the critical redox pair, NAD+ and NADH, for
cellular energy metabolism. In addition, NAD+ is the precursor for de novo NADP+ synthesis …
cellular energy metabolism. In addition, NAD+ is the precursor for de novo NADP+ synthesis …