Vascular access is the lifeline for patients on hemodialysis. Arteriovenous fistulas (AVFs) are
the preferred vascular access, but AVF maturation failure remains a significant clinical …

The development of venous intimal hyperplasia (IH) has been historically associated with
failure of arteriovenous fistulas (AVFs) used for hemodialysis. This long-standing …

Background: Arteriovenous fistula dysfunction is a widely disputed subject in the scientific
literature on end-stage kidney disease (ESKD). The main cause of mortality and morbidity in …

自体动静脉内瘘功能障碍是血液透析患者常见的并发症, 新生内膜异常增生和血管向外重塑障碍
导致静脉流出道狭窄是其最常见原因. 由于目前对内瘘功能障碍的病理生理机制缺乏足够认识 …

Arteries and veins develop different types of occlusive diseases and respond differently to
injury. The biological reasons for this discrepancy are not well understood, which is a …

Chronic kidney disease (CKD) induces the failure of arteriovenous fistulas (AVFs) and
promotes the differentiation of vascular adventitial GLI1-positive mesenchymal stem cells …

Introduction The molecular transformation of the human preaccess vein after arteriovenous
fistula (AVF) creation is poorly understood. This limits our ability to design efficacious …

The venous system has been historically understudied despite its critical roles in blood
distribution, heart function, and systemic immunity. This study dissects the microanatomy of …

Background Arteriovenous fistula (AVF) maturation failure is a main limitation of vascular
access. Maturation is determined by the intricate balance between outward remodeling and …

Neointimal cells are an elusive population with ambiguous origins, functions, and states of
differentiation. Expansion of the venous intima in arteriovenous fistula (AVF) is one of the …