Experimental liver injury with hepatocelluar necrosis and abnormal liver tests is caused by
exposure to heavy metals (HMs) like aluminum, arsenic, beryllium, cadmium, chromium …

This review summarizes the literature describing the molecular mechanisms of arsenic-
induced oxidative stress, its relevant biomarkers, and its relation to various diseases …

Occupational or environmental exposures to heavy metals produce several adverse health
effects. The common mechanism determining their toxicity and carcinogenicity is the …

Arsenic (As) is found in waters such as seawater, warm springs, groundwater, rivers, and
lakes. In aquatic environments, As occurs as a mixture of arsenate and arsenite, with …

Arsenic trioxide has shown substantial efficacy in treating both newly diagnosed and
relapsedpatients with acute promyelocytic leukemia (APL). As a single agent, it induces …

Apoptosis is an evolutionary conserved homeostatic process involved in distinct
physiological processes including organ and tissue morphogenesis, development and …

Occupational and environmental exposures to metals are associated with the development
of various cancers. Although carcinogenesis caused by metals has been intensively …

The past decade has seen an intense focus on mechanisms of apoptosis. Many important
observations on the various signaling pathways mediating apoptotic cell death have been …

Worldwide, there are more than 10 million new cancer cases each year, and cancer is the
cause of approximately 12% of all deaths. Given this, a large number of epidemiologic …

Arsenic, one of the most significant hazards in the environment affecting millions of people
around the world, is associated with several diseases including cancers of skin, lung, urinary …