Effects of choline containing phospholipids on the neurovascular unit: A review
The roles of choline and of choline-containing phospholipids (CCPLs) on the maintenance
and progress of neurovascular unit (NVU) integrity are analyzed. NVU is composed of …
and progress of neurovascular unit (NVU) integrity are analyzed. NVU is composed of …
[HTML][HTML] Phosphatidylcholine (PCL) fortified nano-phytopharmaceuticals for improvement of therapeutic efficacy
DU Kapoor, M Gaur, A Parihar, BG Prajapati… - EXCLI …, 2023 - ncbi.nlm.nih.gov
Phytopharmaceuticals, derived from plants, are increasingly recognized for their potential
therapeutic benefits. However, their effectiveness is often hindered by challenges such as …
therapeutic benefits. However, their effectiveness is often hindered by challenges such as …
Spatially resolved co-imaging of polyhalogenated xenobiotics and endogenous metabolites reveals xenobiotic-induced metabolic alterations
Y Huang, H Shang, C Wang, H Cui… - Environmental …, 2023 - ACS Publications
A large group of polyhalogenated compounds has been added to the list of persistent
organic pollutants in a global convention endorsed by over 100 nations. Once entering the …
organic pollutants in a global convention endorsed by over 100 nations. Once entering the …
[HTML][HTML] Tiagabine suppresses pentylenetetrazole-induced seizures in mice and improves behavioral and cognitive parameters by modulating BDNF/TrkB expression …
Abstract Tiagabine (Tia), a new-generation antiseizure drug that mimics the GABAergic
signaling by inhibiting GABA transporter type-1, is the least studied molecule in chronic …
signaling by inhibiting GABA transporter type-1, is the least studied molecule in chronic …
[HTML][HTML] Management and treatment of traumatic brain injuries
S Jha, P Ghewade - Cureus, 2022 - ncbi.nlm.nih.gov
Traumatic brain injuries (TBI) are one of the main reasons for death in recent years
worldwide or globally. They are the number one cause of death for both civilians and military …
worldwide or globally. They are the number one cause of death for both civilians and military …
[HTML][HTML] Combination of levetiracetam with sodium selenite prevents pentylenetetrazole-induced kindling and behavioral comorbidities in rats
Introduction The pentylenetetrazol (PTZ)-induced kindling model acts through the
antagonism of central GABA A receptors and is one of the most widely used experimental …
antagonism of central GABA A receptors and is one of the most widely used experimental …
An exploratory study on lipidomic profiles in a cohort of individuals with posttraumatic stress disorder
Posttraumatic stress disorder (PTSD) can develop after trauma exposure. Some studies
report that women develop PTSD at twice the rate of men, despite greater trauma exposure …
report that women develop PTSD at twice the rate of men, despite greater trauma exposure …
Demaghi, a polyherbal formulation, mitigates aluminum chloride-induced neurological impairment in mice: Insights from phytochemical analysis and behavioral …
Herbal products have been very popular in Pakistan for their curative significance against
various disorders. Demaghi (DEMG) is a widely used herbal product claimed to own natural …
various disorders. Demaghi (DEMG) is a widely used herbal product claimed to own natural …
An Atlas of the Quantitative Protein Expression of Anti-Epileptic-Drug Transporters, Metabolizing Enzymes and Tight Junctions at the Blood–Brain Barrier in Epileptic …
R Sato, K Ohmori, M Umetsu, M Takao, M Tano… - Pharmaceutics, 2021 - mdpi.com
The purpose of the present study was to quantitatively elucidate the levels of protein
expression of anti-epileptic-drug (AED) transporters, metabolizing enzymes and tight …
expression of anti-epileptic-drug (AED) transporters, metabolizing enzymes and tight …
Citicoline for the management of patients with traumatic brain injury in the acute phase: A systematic review and meta-analysis
JJ Secades, H Trimmel, B Salazar, JA González - Life, 2023 - mdpi.com
Background: Citicoline or CDP-choline is a neuroprotective/neurorestorative drug used in
several countries for the treatment of traumatic brain injury (TBI). Since the publication of the …
several countries for the treatment of traumatic brain injury (TBI). Since the publication of the …