Neuropeptides comprise the most diverse category of neurochemicals in the brain, playing
critical roles in a wide range of physiological and pathophysiological processes. Monitoring …

Methods rooted in chemical biology have contributed significantly to studies of integral
membrane proteins. One recent key approach has been the application of genetic code …

Immunosuppressants are clinically approved drugs to treat the potential rejection of
transplanted organs and require frequent monitoring due to their narrow therapeutic …

Abstract Nociceptin/orphanin-FQ (N/OFQ) is a recently appreciated critical opioid peptide
with key regulatory functions in several central behavioral processes including motivation …

Abstract Class-B1 G-protein-coupled receptors (GPCRs) are an important family of clinically
relevant drug targets that remain difficult to investigate via high-throughput screening and in …

Understanding how neuronal networks generate complex behavior is one of the major goals
of Neuroscience. Neurotransmitter and Neuromodulators are crucial for information flow …

One of the major challenges in molecular neuroscience today is to accurately monitor
neurotransmitters, neuromodulators, peptides, and various other biomolecules in the brain …

Beta-adrenergic receptors (βARs) are G protein-coupled receptors (GPCRs) that mediate
catecholamine hormone-induced stress responses, such as elevation of heart rate. Besides …

Live imaging techniques have revolutionized our understanding of paracrine signaling, a
crucial form of cell-to-cell communication in biological processes. This review examines …

Abstract Neurotransmitters (NTs) and neuromodulators (NMs) play vital roles in various
physiological and pathological processes. To better understand the transmission …