Prevalence and mortality rate of sepsis among adults admitted to hospitals in sub-Saharan Africa: a systematic review and meta-analysis

GT Kiya, Z Mekonnen, T Melaku, E Tegene… - Journal of Hospital …, 2024 - Elsevier
Due to abundant pathogen diversity and mounting antimicrobial resistance, sepsis is more
common in sub-Saharan Africa (sSA). However, there is a lack of consistent reports …

Persistence is key: unresolved immune dysfunction is lethal in both COVID-19 and non-COVID-19 sepsis

AY An, A Baghela, P Zhang, R Falsafi, AH Lee… - Frontiers in …, 2023 - frontiersin.org
Introduction Severe COVID-19 and non-COVID-19 pulmonary sepsis share
pathophysiological, immunological, and clinical features, suggesting that severe COVID-19 …

Predicting mortality in febrile adults: comparative performance of the MEWS, qSOFA, and UVA scores using prospectively collected data among patients in four health …

S Lal, M Luangraj, SH Keddie, EA Ashley… - …, 2024 - thelancet.com
Background Clinical severity scores can identify patients at risk of severe disease and death,
and improve patient management. The modified early warning score (MEWS), the quick …

Unsupervised Classification of the Host Response Identifies Dominant Pathobiological Signatures of Sepsis in Sub-Saharan Africa

MJ Cummings, JJ Lutwama, N Owor… - American Journal of …, 2024 - atsjournals.org
Rationale: The global burden of sepsis is concentrated in sub-Saharan Africa, where inciting
pathogens are diverse and HIV co-infection is a major driver of poor outcomes. Biological …

Predictors of mortality for perforated peptic ulcer disease in Malawi

SJ An, D Davis, L Kayange, J Gallaher… - The American Journal of …, 2023 - Elsevier
Background Mortality from perforated peptic ulcer disease (PUD) remains high, especially in
sub-Saharan Africa. We sought to identify predictors of mortality following surgery for …

Antimicrobial resistance patterns of isolates from bloodstream infections at Jinja Regional Referral Hospital: A cross-sectional study

F Lwigale - Access Microbiology, 2024 - microbiologyresearch.org
Background Bloodstream infections are common acute syndromes of variable origin with
high chances for extreme health effects including death. This underscores the essence for …