Copper coordination compounds as biologically active agents

O Krasnovskaya, A Naumov, D Guk, P Gorelkin… - International Journal of …, 2020 - mdpi.com
Copper-containing coordination compounds attract wide attention due to the redox activity
and biogenicity of copper ions, providing multiple pathways of biological activity. The …

Nitroimidazole-containing compounds and their antibacterial and antitubercular activities

J Zhang, Y Ba, S Wang, H Yang, X Hou, Z Xu - European journal of …, 2019 - Elsevier
Infections especially tuberculosis caused by various bacteria including mycobacteria result
in millions of lives every year, but the control of bacterial infections is challenged by the …

Synthesis, crystal structure, Hirshfeld surface analysis, DFT, molecular docking and molecular dynamic simulation studies of (E)-2, 6-bis (4-chlorophenyl)-3-methyl-4 …

LA Anthony, D Rajaraman, G Sundararajan… - Journal of Molecular …, 2022 - Elsevier
A novel drug to treat SARS-CoV-2 infections and hydroxyl chloroquine analogue,(E)-2, 6-bis
(4-chlorophenyl)-3-methyl-4-(2-(2, 4, 6-trichlorophenyl) hydrazono) piperidine (BCMTP) …

Synthesis, characterization, anticancer and in silico studies of a pyrazole-tethered thiazolidine-2,4-dione derivative

MM Alshammari, R Soury, KM Alenezi… - Journal of …, 2022 - Taylor & Francis
A new pyrazole-tethered thiazolidine-2, 4-dione derivative (8) has been synthesized by the
Knoevenagel condensation of 3-(4-nitrophenyl)-1-phenyl-1 H-pyrazole-4-carbaldehyde (4) …

5-Fluorouracil (5-FU)-based Aza-Michael addition product: A selective carbonic anhydrase IX inhibitor

M Mushtaque, F Avecilla, I Ahmad, AM Alharbi… - Journal of Molecular …, 2021 - Elsevier
Abstract A new 5-fluorouracil (5-FU) derivative (3) has been obtained by Aza-Michael
addition reaction between 5-FU and acrylonitrile. The structure of the compound was …

Synthesis of Mixed Arylalkyl Tertiary Phosphines via the Grignard Approach

A Haque, KM Alenezi, HE Moll, MS Khan, WY Wong - Molecules, 2022 - mdpi.com
Trialkyl and triaryl phosphines are important classes of ligands in the field of catalysis and
materials research. The wide usability of these low-valent phosphines has led to the design …

[HTML][HTML] Nanomolar photodynamic activity of porphyrins bearing 1, 4, 7-trioxanonyl and 2-methyl-5-nitroimidazole moieties against cancer cells

M Wierzchowski, D Łażewski, T Tardowski… - … of Photochemistry and …, 2020 - Elsevier
Despite the continuous development of medicine, there is still a lack of effective and fully
safe protocols for the treatment of neoplastic diseases. The drug-drug conjugates approach …

Síntesis y caracterización de ligandos derivados de piridoxal y sus complejos de Cu (II) y estudio de su interacción con el ADN y otras dianas biológicas

L Ramos Pan - 2022 - ruc.udc.es
Los ligandos hidrazona derivados de piridoxal y sus complejos metálicos han generado un
gran interés en química médica durante la última década debido a la gran versatilidad de …

Desenvolvimento e validação de método indicativo de estabilidade para quantificação de secnidazol e compostos relacionados por cromatografia líquida de alta …

LF Maestrelo - 2020 - tede.unioeste.br
Quando o consumidor retira um medicamento na farmácia ou drogaria, dificilmente tem a
percepção do longo caminho percorrido até este ser obtido. A cadeia de fabricação dos …

Complejos de Molibdeno susceptibles de interaccionar con el ADN con potenciales aplicaciones antitumorales

M Riopedre Fernández - 2019 - ruc.udc.es
La investigación en busca de compuestos metálicos con utilidad farmacológica ha crecido
enormemente en los últimos años, debido al gran espectro de nuevas posibilidades que …