Biological membranes are tricky to investigate. They are complex in terms of molecular
composition and structure, functional over a wide range of time scales, and characterized by …

Cholesterol modulates the bilayer structure of biological membranes in multiple ways. It
changes the fluidity, thickness, compressibility, water penetration and intrinsic curvature of …

The plasma membrane of eukaryotic cells contains several types of lipids displaying high
biochemical variability in both their apolar moiety (eg, the acyl chain of glycerolipids) and …

Lipid–protein interactions in cells are involved in various biological processes, including
metabolism, trafficking, signaling, host–pathogen interactions, and transmembrane …

The membrane bilayer has a significant influence over the proteins embedded within it. G
protein-coupled receptors (GPCRs) form a large group of membrane proteins with a vast …

The dimerization or even oligomerization of G protein coupled receptors (GPCRs) causes
ongoing, controversial debates about its functional role and the coupled biophysical …

The β 2-adrenergic receptor is an important member of the G-protein-coupled receptor
(GPCR) superfamily, whose stability and function are modulated by membrane cholesterol …

The function of several G protein–coupled receptors (GPCRs) exhibits cholesterol sensitivity.
Cholesterol sensitivity of GPCRs could be attributed to specific sequence and structural …

G protein-coupled receptors (GPCRs) are the largest class of molecules involved in signal
transduction across cell membranes and represent major targets in the development of …

Lipids play a diverse and critical role in cellular processes in all tissues. The unique lipid
composition of nerve membranes is particularly interesting because it contains, among other …