Alzheimer's disease (AD) is the most common cause of dementia. Despite this, clear
pathophysiology for AD has not been confirmed, and effective treatments are still not …

Studies suggest that tau deposition starts in the anterolateral entorhinal cortex (EC) with
normal aging, and that the presence of β-amyloid (Aβ) facilitates its spread to neocortex …

Objective Endothelial dysfunction is an early and prevalent pathology in Alzheimer disease
(AD). We here investigate the value of vascular endothelial‐cadherin (VEC) as a …

Background Disease-modifying agents to counteract cognitive impairment in older age
remain elusive. Hence, identifying modifiable factors promoting resilience, as the capacity of …

Abstract Idiopathic Normal Pressure Hydrocephalus (iNPH)—the leading cause of reversible
dementia in aging—is characterized by ventriculomegaly and gait, cognitive and urinary …

The aim of this study was to assess the diagnostic validity of a deep learning-based method
estimating brain age based on magnetic resonance imaging (MRI) and to compare it with …

Previous studies have demonstrated that functional connectivity (FC) of different brain
regions in resting state function MRI were abnormal in patients suffering from mild cognitive …

Background. Psychophysiological and cognitive tests as well as other functional studies can
detect pre-symptomatic stages of dementia. When assembled with structural data, cognitive …

Background and Objectives Neurofilament light chain (NfL) in blood is a sensitive but
nonspecific marker of brain injury. This study sought to evaluate associations between NfL …

Here we assessed changes in subcortical volumes in alcohol use disorder (AUD). A simple
morphometry-based classifier (MC) was developed to identify subcortical volumes that …