Advances and challenges in metatranscriptomic analysis

M Shakya, CC Lo, PSG Chain - Frontiers in genetics, 2019 - frontiersin.org
Sequencing-based analyses of microbiomes have traditionally focused on addressing the
question of community membership and profiling taxonomic abundance through amplicon …

Demystifying emerging bulk RNA-Seq applications: the application and utility of bioinformatic methodology

AS Thind, I Monga, PK Thakur, P Kumari… - Briefings in …, 2021 - academic.oup.com
Significant innovations in next-generation sequencing techniques and bioinformatics tools
have impacted our appreciation and understanding of RNA. Practical RNA sequencing …

[HTML][HTML] Current understanding of plant-microbe interaction through the lenses of multi-omics approaches and their benefits in sustainable agriculture

D Diwan, MM Rashid, A Vaishnav - Microbiological Research, 2022 - Elsevier
The success of sustainable agricultural practices has now become heavily dependent on the
interactions between crop plants and their associated microbiome. Continuous …

Metatranscriptomics: an approach for retrieving novel eukaryotic genes from polluted and related environments

A Mukherjee, MS Reddy - 3 Biotech, 2020 - Springer
Metatranscriptomics, a subset of metagenomics, provides valuable information about the
whole gene expression profiling of complex microbial communities of an ecosystem …

[HTML][HTML] Mapping human pathogens in wastewater using a metatranscriptomic approach

J Carneiro, F Pascoal, M Semedo, D Pratas… - Environmental …, 2023 - Elsevier
The monitoring of cities' wastewaters for the detection of potentially pathogenic viruses and
bacteria has been considered a priority during the COVID-19 pandemic to monitor public …

Metaomics in clinical laboratory: potential driving force for innovative disease diagnosis

L Wang, F Li, B Gu, P Qu, Q Liu, J Wang… - Frontiers in …, 2022 - frontiersin.org
Currently, more and more studies suggested that reductionism was lack of holistic and
integrative view of biological processes, leading to limited understanding of complex …

[HTML][HTML] MIntO: a modular and scalable pipeline for microbiome metagenomic and metatranscriptomic data integration

C Saenz, E Nigro, V Gunalan… - Frontiers in …, 2022 - frontiersin.org
Omics technologies have revolutionized microbiome research allowing the characterization
of complex microbial communities in different biomes without requiring their cultivation. As a …

De novo assembly and annotation of the vaginal metatranscriptome associated with bacterial vaginosis

WK Cho, Y Jo, S Jeong - International Journal of Molecular Sciences, 2022 - mdpi.com
The vaginal microbiome plays an important role in women's health and disease. Here we
reanalyzed 40 vaginal transcriptomes from a previous study of de novo assembly (metaT …

MOSCA 2.0: A bioinformatics framework for metagenomics, metatranscriptomics and metaproteomics data analysis and visualization

JC Sequeira, V Pereira, MM Alves… - Molecular Ecology …, 2024 - Wiley Online Library
The analysis of meta‐omics data requires the utilization of several bioinformatics tools and
proficiency in informatics. The integration of multiple meta‐omics data is even more …

Intraintestinal analysis of the functional activity of microbiomes and its application to the common marmoset intestine

M Uehara, T Inoue, M Kominato, S Hase, E Sasaki… - Msystems, 2022 - Am Soc Microbiol
The intestinal microbiome is closely related to host health, and metatranscriptomic analysis
can be used to assess the functional activity of microbiomes by quantifying microbial gene …