The contribution of wheat to human diet and health

PR Shewry, SJ Hey - Food and energy security, 2015 - Wiley Online Library
Wheat is the most important staple crop in temperate zones and is in increasing demand in
countries undergoing urbanization and industrialization. In addition to being a major source …

Towards CRISPR/Cas crops–bringing together genomics and genome editing

A Scheben, F Wolter, J Batley, H Puchta… - New …, 2017 - Wiley Online Library
With the rapid increase in the global population and the impact of climate change on
agriculture, there is a need for crops with higher yields and greater tolerance to abiotic …

Targeted, random mutagenesis of plant genes with dual cytosine and adenine base editors

C Li, R Zhang, X Meng, S Chen, Y Zong, C Lu… - Nature …, 2020 - nature.com
Targeted saturation mutagenesis of crop genes could be applied to produce genetic variants
with improved agronomic performance. However, tools for directed evolution of plant genes …

Precise base editing in rice, wheat and maize with a Cas9-cytidine deaminase fusion

Y Zong, Y Wang, C Li, R Zhang, K Chen, Y Ran… - Nature …, 2017 - nature.com
Targeted base editing in plants without the need for a foreign DNA donor or double-stranded
DNA cleavage would accelerate genome modification and breeding in a wide array of crops …

Simultaneous modification of three homoeologs of TaEDR1 by genome editing enhances powdery mildew resistance in wheat

Y Zhang, Y Bai, G Wu, S Zou, Y Chen, C Gao… - The Plant …, 2017 - Wiley Online Library
Wheat (Triticum aestivum L.) incurs significant yield losses from powdery mildew, a major
fungal disease caused by Blumeria graminis f. sp. tritici (Bgt). enhanced disease resistance1 …

Simultaneous editing of three homoeoalleles in hexaploid bread wheat confers heritable resistance to powdery mildew

Y Wang, X Cheng, Q Shan, Y Zhang, J Liu, C Gao… - Nature …, 2014 - nature.com
Sequence-specific nucleases have been applied to engineer targeted modifications in
polyploid genomes, but simultaneous modification of multiple homoeoalleles has not been …

Precision genome engineering through adenine base editing in plants

BC Kang, JY Yun, ST Kim, YJ Shin, J Ryu, M Choi… - Nature plants, 2018 - nature.com
The recent development of adenine base editors (ABEs) has enabled efficient and precise A-
to-G base conversions in higher eukaryotic cells. Here, we show that plant-compatible ABE …

High‐amylose starches to bridge the “Fiber Gap”: development, structure, and nutritional functionality

H Li, MJ Gidley, S Dhital - … Reviews in Food Science and Food …, 2019 - Wiley Online Library
Although high‐amylose starches are not a recent innovation, their popularity in recent years
has been increasing due to their unique functional properties and enhanced nutritional …

Cereal endosperms: development and storage product accumulation

J Liu, MW Wu, CM Liu - Annual review of plant biology, 2022 - annualreviews.org
The persistent triploid endosperms of cereal crops are the most important source of human
food and animal feed. The development of cereal endosperms progresses through …

Comparison of T7E1 and surveyor mismatch cleavage assays to detect mutations triggered by engineered nucleases

L Vouillot, A Thélie, N Pollet - G3: Genes, Genomes, Genetics, 2015 - academic.oup.com
Genome editing using engineered nucleases is used for targeted mutagenesis. But because
genome editing does not target all loci with similar efficiencies, the mutation hit-rate at a …