Brainstem dysfunction in critically ill patients

S Benghanem, A Mazeraud, E Azabou, V Chhor… - Critical Care, 2020 - Springer
The brainstem conveys sensory and motor inputs between the spinal cord and the brain,
and contains nuclei of the cranial nerves. It controls the sleep-wake cycle and vital functions …

Deep brain stimulation of the thalamus restores signatures of consciousness in a nonhuman primate model

J Tasserie, L Uhrig, JD Sitt, D Manasova, M Dupont… - Science …, 2022 - science.org
Loss of consciousness is associated with the disruption of long-range thalamocortical and
corticocortical brain communication. We tested the hypothesis that deep brain stimulation …

Toward a coherent structuration of disorders of consciousness expertise at a country scale: A proposal for France

L Naccache, J Luauté, S Silva, JD Sitt, B Rohaut - Revue Neurologique, 2022 - Elsevier
Probing consciousness and cognitive abilities in non-communicating patients is one of the
most challenging diagnostic issues. A fast growing medical and scientific literature explores …

Perturbations in dynamical models of whole-brain activity dissociate between the level and stability of consciousness

Y Sanz Perl, C Pallavicini, I Pérez Ipiña… - PLoS computational …, 2021 - journals.plos.org
Consciousness transiently fades away during deep sleep, more stably under anesthesia,
and sometimes permanently due to brain injury. The development of an index to quantify the …

Differential cortical network engagement during states of un/consciousness in humans

R Zelmann, AC Paulk, F Tian, GAB Villegas, JD Peralta… - Neuron, 2023 - cell.com
What happens in the human brain when we are unconscious? Despite substantial work, we
are still unsure which brain regions are involved and how they are impacted when …

Combined behavioral and electrophysiological evidence for a direct cortical effect of prefrontal tDCS on disorders of consciousness

B Hermann, F Raimondo, L Hirsch, Y Huang… - Scientific reports, 2020 - nature.com
Severe brain injuries can lead to long-lasting disorders of consciousness (DoC) such as
vegetative state/unresponsive wakefulness syndrome (VS/UWS) or minimally conscious …

Noninvasive brain stimulation for patients with a disorder of consciousness: a systematic review and meta-analysis

Y Feng, J Zhang, Y Zhou, Z Bai, Y Yin - Reviews in the …, 2020 - degruyter.com
Noninvasive brain stimulation (NIBS) techniques have been used to facilitate the recovery
from prolonged unconsciousness as a result of brain injury. The aim of this study is to …

Sleep patterns correlates with the efficacy of tDCS on post-stroke patients with prolonged disorders of consciousness

J Yu, Y Wu, B Wu, C Xu, J Cai, X Wen, F Meng… - Journal of Translational …, 2022 - Springer
Background The subclassification of prolonged disorders of consciousness (DoC) based on
sleep patterns is important for the evaluation and treatment of the disease. This study …

Clinical decision on disorders of consciousness after acquired brain injury: stepping forward

RZ Zheng, ZX Qi, Z Wang, ZY Xu, XH Wu, Y Mao - Neuroscience Bulletin, 2023 - Springer
Major advances have been made over the past few decades in identifying and managing
disorders of consciousness (DOC) in patients with acquired brain injury (ABI), bringing the …

The role of plasticity in the recovery of consciousness

S Bagnato - Handbook of Clinical Neurology, 2022 - Elsevier
Disorders of consciousness (DOCs), ie, coma, vegetative state, and minimally conscious
state are the consequences of a severe brain injury that disrupts the brain ability to generate …