Our knowledge about the fundamental aspects of biofilm biology, including the mechanisms
behind the reduced antimicrobial susceptibility of biofilms, has increased drastically over the …

Biofilm-associated infections are difficult to treat and eradicate because of their increased
antimicrobial tolerance. In vitro biofilm models have enabled the high throughput testing of …

Biofilms are increasingly recognised as a critical global issue in a multitude of industries
impacting health, food and water security, marine sector, and industrial processes resulting …

The prevalence of chronic, non-healing skin wounds in the general population, most notably
diabetic foot ulcers, venous leg ulcers and pressure ulcers, is approximately 2% and is …

There is an increasing use of non‐medicated wound dressing with claims of irreversible
bacterial binding. Most of the data are from in vitro models which lack clinical relevance. This …

Studies have reported that the constituents of the wound microenvironment are likely to have
critical roles in the degradation and fate of the polymeric matrix and the compounds …

Chronic wounds present a global healthcare challenge and are increasing in prevalence,
with bacterial biofilms being the primary roadblock to healing in most cases. A systematic …

The staphylococcal biofilm-based infections of wounds still pose a significant therapeutical
challenge. Treated improperly, they increase the risk of limb amputation or even death of the …

Healing and treatment of chronic wounds are often complicated due to biofilm formation by
pathogens. Here, the efficacy of plasma activated water (PAW) as a pre-treatment strategy …

Current standards insufficiently acknowledge the influence of the wound micro-environment
on the efficacy of antimicrobial agents. To address this, octenidine/phenoxyethanol …