Cancer is one of the leading causes of mortality worldwide. Currently available anticancer
therapeutic strategies are not able to improve the survival rate of patients over the past few …

Cancer is a worldwide disease that causes millions of cases of mortality and morbidity. The
major problem associated with the cancer is its resistance to conventional therapy and a …

Natural products have a broad diversity of multidimensional chemical formations, which play
an important role, and indicate the crucial nature as a golden source for gaining herbal drug …

Malathion is a potent organophosphate insecticide that inhibits acetylcholinesterase (AChE)
enzyme. Our experimental objective was to investigate the beneficial effects of diallyl …

Objective Treatment with the chemotherapeutic agent, doxorubicin (DOX), is limited by side
effects. We have previously demonstrated that fasudil, a Rho/ROCK inhibitor, has …

The aberration of programmed cell death including cell death associated with
autophagy/mitophagy, apoptosis, necroptosis, pyroptosis, and ferroptosis can be observed …

We aimed to investigate the impact of thymoquinone (TQ), on sphingolipid metabolites, ER
stress and apoptotic pathways in MCF-7 and HepG2 cancer cells. Antiproliferative effect was …

The long-term success of standard anticancer monotherapeutic strategies has been
hampered by intolerable side effects, resistance to treatment and cancer relapse. These …

ABSTRACT Introduction: Thymoquinone (TQ), 2-isopropyl-5-methylbenzo-1, 4-quinone, the
main active constituent of Nigella sativa (NS) plant, has been proven to be of great …

Cancer causes a considerable amount of mortality in the world, while arthritis is an
immunological dysregulation with multifactorial pathogenesis including genetic and …