Asthma is a complex disease of the lungs, which is characterized by airway inflammation
and airway hyperresponsiveness (AHR). Alveolar macrophages (AMs), one of the prominent …

Lipoxygenase Monooxygenase Phospholipase Oxygen Radicals Leukocyte Pathways
Eosinophils Neutrophils Mast Cells Mononuclear Phagocytes Epithelial Cell Pathways …

Suggestive evidence indicates that immunoglobulin E (IgE)-dependent activation of
mononuclear phagocytes plays an important pathogenic role in allergic tissue inflammation …

To investigate the contribution of interleukin-4 (IL-4) to airway inflammation in vivo and to
explore directly its relationship to airway reactivity, we created transgenic mice in which the …

Asthma is characterized by bronchial mucosal inflammation. Although allergen-induced
activation of cells binding allergen-specific immunoglobulin E (IgE) through high-affinity …

rIL-4 (B cell stimulatory factor 1) induces the expression of Fc epsilon R2/CD23 on normal
human monocytes (Mo). Fc epsilon R2/CD23 induction was detectable both by flow …

Immunohistochemical Characterization of the Cellular Infiltration in Asthmatic Bronchi Page 1
Immunohistochemical Characterization of the Cellular Infiltration in Asthmatic Bronchi1 - 3 RN …

More than 50 million Americans, one out of five, suffer from hay fever, asthma, and other
allergic diseases. Many of these conditions are caused by exposure to allergens in indoor …

Idiopathic pulmonary fibrosis (IPF) is a progressive disorder characterized by inflammation,
fibroblast proliferation, and accumulation of extracellular matrix proteins. Leukotrienes (LTs) …

Inhalation of an antigen, ovalbumin (OVA), in the absence of adjuvant has been
demonstrated to induce an immune response that is associated with increased airway …