Radiopharmaceuticals for PET and SPECT imaging: a literature review over the last decade

G Crișan, NS Moldovean-Cioroianu… - International journal of …, 2022 - mdpi.com
Positron emission tomography (PET) uses radioactive tracers and enables the functional
imaging of several metabolic processes, blood flow measurements, regional chemical …

Review on 99mTc radiopharmaceuticals with emphasis on new advancements

A Duatti - Nuclear medicine and biology, 2021 - Elsevier
Rapid imaging acquisition, high spatial resolution and sensitivity, powered by
advancements in solid-state detector technology, are significantly changing the perspective …

Technetium (I) carbonyl complexes for nuclear medicine: Coordination-chemical aspect

GV Sidorenko, AE Miroslavov, MY Tyupina - Coordination Chemistry …, 2023 - Elsevier
Studies concerning the development of radiopharmaceuticals based on the Tc (I) carbonyl
core are considered from the coordination-chemical viewpoint. The coordination behavior of …

Chelators and metal complex stability for radiopharmaceutical applications

NC Okoye, JE Baumeister, F Najafi Khosroshahi… - Radiochimica …, 2019 - degruyter.com
Diagnostic and therapeutic nuclear medicine relies heavily on radiometal nuclides. The
most widely used and well-known radionuclide is technetium-99m (99mTc), which has …

Bifunctional chelators for radiorhenium: Past, present and future outlook

DR Melis, AR Burgoyne, M Ooms… - RSC Medicinal Chemistry, 2022 - pubs.rsc.org
Targeted radionuclide therapy (TRNT) is an ever-expanding field of nuclear medicine that
provides a personalised approach to cancer treatment while limiting toxicity to normal …

Spectroscopic and molecular docking study of the interaction between neutral Re (I) tetrazolate complexes and bovine serum albumin

J Lazniewska, M Agostino, SM Hickey… - … A European Journal, 2021 - Wiley Online Library
Re (I) complexes have potential in biomedical sciences as imaging agents, diagnostics and
therapeutics. Thus, it is crucial to understand how Re (I) complexes interact with carrier …

1,4,7-Triazacyclononane-Based Chelators for the Complexation of [186Re]Re- and [99mTc]Tc-Tricarbonyl Cores

R Hoerres, HM Hennkens - Inorganic Chemistry, 2023 - ACS Publications
Metal complexes with the general formula [MI (CO) 3 (k3-L)]+, where M= Re, 186Re, or
99mTc and L= 1, 4, 7-triazacyclononane (TACN), NOTA, or NODAGA chelators, have …

Somatostatin receptor targeting with hydrophilic [99mTc/186Re] Tc/Re-tricarbonyl NODAGA and NOTA complexes

G Makris, M Kuchuk, F Gallazzi, SS Jurisson… - Nuclear medicine and …, 2019 - Elsevier
Introduction The aim of this work was to develop diagnostic (99m Tc) and therapeutic (186
Re) agents for targeting somatostatin receptor (SSTR)-positive neuroendocrine tumors …

Novel [99mTc]-Tricarbonyl-NOTA-Conjugated Lactam-Cyclized Alpha-MSH Peptide with Enhanced Melanoma Uptake and Reduced Renal Uptake

Z Qiao, J Xu, R Gonzalez, Y Miao - Molecular pharmaceutics, 2020 - ACS Publications
The purpose of this study was to examine the melanoma targeting and imaging properties of
99mTc (CO) 3-NOTA-GGNle-CycMSHhex {1, 4, 7-triazacyclononane-1, 4, 7-triyl-triacetic …

Development and Preclinical Evaluation of 99mTc- and 186Re-Labeled NOTA and NODAGA Bioconjugates Demonstrating Matched Pair Targeting of GRPR …

G Makris, RP Bandari, M Kuchuk, SS Jurisson… - Molecular Imaging and …, 2021 - Springer
Purpose The goal of this work was to develop hydrophilic gastrin-releasing peptide receptor
(GRPR)-targeting complexes of the general formula fac-[M (CO) 3 (L)]+[M= nat Re, 99m Tc …