Circular dichroism sensing: Strategies and applications

JSSK Formen, JR Howard, EV Anslyn… - Angewandte Chemie …, 2024 - Wiley Online Library
The analysis of the absolute configuration, enantiomeric composition, and concentration of
chiral compounds are frequently encountered tasks across the chemical and health …

Extendable stapling of unprotected peptides by crosslinking two amines with o-phthalaldehyde

B Li, L Wang, X Chen, X Chu, H Tang, J Zhang… - Nature …, 2022 - nature.com
Peptide modification methods that do not rely on the cysteine residue are underdeveloped,
and their development could greatly expand the current toolbox for peptide chemistry …

Bioconjugation via Hetero‐Selective Clamping of Two Different Amines with ortho‐Phthalaldehyde

X Chu, B Li, HY Liu, X Sun, X Yang, G He… - Angewandte …, 2023 - Wiley Online Library
Amino groups are common in both natural and synthetic compounds and offer a very
attractive class of endogenous handles for bioconjugation. However, the ability to …

Efficacy of 2-nitrobenzylidene-hydrazine-based selective and rapid sensor for Cu2+ ions, histidine, and tyrosine: Spectral and computational study

B Mohan, K Modi, J Parikh, S Ma, S Kumar… - … of Photochemistry and …, 2022 - Elsevier
Spectroscopic detection of metal ions and amino acids has gained significant attention
owing to the public health domain. In this study, we design and synthesize a rapid UV …

Carborane-Cluster-Wrapped Copper Cluster with Cyclodextrin-like Cavities for Chiral Recognition

JH Huang, YJ Liu, Y Si, Y Cui, XY Dong… - Journal of the …, 2024 - ACS Publications
Chiral atomically precise metal clusters, known for their remarkable chiroptical properties,
hold great potential for applications in chirality recognition. However, advancements in this …

Noncovalent induced circular dichroism sensors based on a chiral metal–organic framework: chiral induction synthesis, quantitative enantioselective sensing and …

Y Zhu, T Ding, X Zhang, Y Zhou, J Yu, X Li… - Inorganic Chemistry …, 2023 - pubs.rsc.org
As an important class of chiral optical sensors, chiral induced circular dichroism (ICD)
sensors have received increasing attention. Herein, a series of monometallic and bimetallic …

Iodine-mediated tryptathionine formation facilitates the synthesis of amanitins

G Yao, CH Knittel, S Kosol, MT Wenz… - Journal of the …, 2021 - ACS Publications
Synthetic methods on the macrocyclization of peptides are of high interest since they
facilitate the synthesis of various types of potentially bioactive compounds, eg addressing …

Simultaneous identification and quantification of amino acids in biofluids by reactive 19 F-tags

YT Chen, B Li, XY Li, JL Chen, CY Cui, K Hu… - Chemical …, 2021 - pubs.rsc.org
A robust method to identify and quantify amino acids close to physiological conditions by 1D
19F NMR was established. Each 19F-derivatized amino acid has its characteristic chemical …

Optical Relay Sensing of Cryptochiral Alcohols Displaying α‐, β‐, γ‐and δ‐Stereocenters or Chirality by Virtue of Isotopic Substitution

JSSK Formen, C Wolf - Angewandte Chemie International …, 2024 - Wiley Online Library
A reaction‐based optical relay sensing strategy that enables accurate determination of the
concentration and enantiomeric ratio (er) of challenging chiral alcohols exhibiting …

Analysis of the amine submetabolome using novel isotope-coded pyrylium salt derivatization and LC-MS: Herbs and cancer tissues as cases

L Liu, GY Bao, SS Zhang, Y Qin, XP Chen… - Analytical …, 2022 - ACS Publications
The amine submetabolome, including amino acids (AAs) and biogenic amines (BAs), is a
class of small molecular compounds exhibiting important physiological activities. Here, a …