Background Selenium is an essential micronutrient that plays a vital role in human health.
The global selenium deficiency stimulates the development of novel selenium compounds …

Abstract Phosphatidylinositol 3-kinase (PI3K)-AKT pathway is one of the most important
kinase signaling networks in the context of cancer development and treatment. Aberrant …

In this study, a versatile tumor-targeted and multi-stimuli-responsive drug delivery vehicle
(Se particle@ porous silica–folic acid–copper sulfide/doxorubicin (Se@ SiO2–FA …

Selenium nanoparticles (SeNPs) have attracted much interest as potential anticancer
nanodrugs. Our previous studies also demonstrated that SeNPs could be developed as …

Cervical cancer is a highly prevalent cancer that affects women around the world. With the
availability of new technologies, researchers have increased their efforts to develop new …

Multi-target intervention and synergistic treatment are critical for the drug development of
Alzheimer's disease (AD) due to its complex and multifactional nature. Oxidative stress and …

The rational design of cancer‐targeted and bioresponsive drug delivery vehicles can
enhance the anticancer efficacy of conventional chemotherapeutics and reduce their …

Although radiotherapy has been extensively applied in cancer treatment, external beam
radiation therapy is still unable to avoid damage to adjacent normal tissues in the process of …

Introduction: Cervical cancer is the second most common cancer and the largest cancer
killer among women in most developing countries including India. Although, various drugs …

An effective chemotherapy is usually subject to an insufficient loading of hydrophobic drugs
as well as severe side effects. In order to address these dilemmas in one formulation, we …