Harnessing multimodal data integration to advance precision oncology
Advances in quantitative biomarker development have accelerated new forms of data-driven
insights for patients with cancer. However, most approaches are limited to a single mode of …
insights for patients with cancer. However, most approaches are limited to a single mode of …
Glioblastoma and other primary brain malignancies in adults: a review
LR Schaff, IK Mellinghoff - Jama, 2023 - jamanetwork.com
Importance Malignant primary brain tumors cause more than 15 000 deaths per year in the
United States. The annual incidence of primary malignant brain tumors is approximately 7 …
United States. The annual incidence of primary malignant brain tumors is approximately 7 …
Vorasidenib in IDH1-or IDH2-mutant low-grade glioma
IK Mellinghoff, MJ Van Den Bent… - … England Journal of …, 2023 - Mass Medical Soc
Background Isocitrate dehydrogenase (IDH)–mutant grade 2 gliomas are malignant brain
tumors that cause considerable disability and premature death. Vorasidenib, an oral brain …
tumors that cause considerable disability and premature death. Vorasidenib, an oral brain …
CBTRUS statistical report: primary brain and other central nervous system tumors diagnosed in the United States in 2015–2019
Abstract The Central Brain Tumor Registry of the United States (CBTRUS), in collaboration
with the Centers for Disease Control and Prevention and the National Cancer Institute, is the …
with the Centers for Disease Control and Prevention and the National Cancer Institute, is the …
Towards a general-purpose foundation model for computational pathology
Quantitative evaluation of tissue images is crucial for computational pathology (CPath) tasks,
requiring the objective characterization of histopathological entities from whole-slide images …
requiring the objective characterization of histopathological entities from whole-slide images …
A clinically applicable integrative molecular classification of meningiomas
Meningiomas are the most common primary intracranial tumour in adults. Patients with
symptoms are generally treated with surgery as there are no effective medical therapies. The …
symptoms are generally treated with surgery as there are no effective medical therapies. The …
Artificial-intelligence-based molecular classification of diffuse gliomas using rapid, label-free optical imaging
Molecular classification has transformed the management of brain tumors by enabling more
accurate prognostication and personalized treatment. However, timely molecular diagnostic …
accurate prognostication and personalized treatment. However, timely molecular diagnostic …
[PDF][PDF] Glioma progression is shaped by genetic evolution and microenvironment interactions
The factors driving therapy resistance in diffuse glioma remain poorly understood. To identify
treatment-associated cellular and genetic changes, we analyzed RNA and/or DNA …
treatment-associated cellular and genetic changes, we analyzed RNA and/or DNA …
Molecular imaging in oncology: Current impact and future directions
The authors define molecular imaging, according to the Society of Nuclear Medicine and
Molecular Imaging, as the visualization, characterization, and measurement of biological …
Molecular Imaging, as the visualization, characterization, and measurement of biological …
CBTRUS statistical report: primary brain and other central nervous system tumors diagnosed in the United States in 2013–2017
Abstract The Central Brain Tumor Registry of the United States (CBTRUS), in collaboration
with the Centers for Disease Control (CDC) and National Cancer Institute (NCI), is the …
with the Centers for Disease Control (CDC) and National Cancer Institute (NCI), is the …