Recent large-scale collaborations are generating major surveys of cell types and
connections in the mouse brain, collecting large amounts of data across modalities, spatial …

Charting an organs' biological atlas requires us to spatially resolve the entire single-cell
transcriptome, and to relate such cellular features to the anatomical scale. Single-cell and …

Basal ganglia play a central role in regulating behavior, but the organization of their outputs
to other brain areas is incompletely understood. We investigate the largest output nucleus …

The basolateral amygdalar complex (BLA) is implicated in behaviors ranging from fear
acquisition to addiction. Optogenetic methods have enabled the association of circuit …

Anatomical atlases in standard coordinates are necessary for the interpretation and
integration of research findings in a common spatial context. However, the two most-used …

To investigate the circuit-level neural mechanisms of behavior, simultaneous imaging of
neuronal activity in multiple cortical and subcortical regions is highly desired. Miniature head …

Abstract 3D standard reference brains serve as key resources to understand the spatial
organization of the brain and promote interoperability across different studies. However …

The human right ventricle is barely monitored during open-chest surgery due to the absence
of intraoperative imaging techniques capable of elaborating its complex function …

Although identifying cell names in dense image stacks is critical in analyzing functional
whole-brain data enabling comparison across experiments, unbiased identification is very …

The segmentation of brain region contours in three dimensions is critical for the analysis of
different brain structures, and advanced approaches are emerging continuously within the …