On RNA-programmable gene modulation as a versatile set of principles targeting muscular dystrophies

S Capelletti, SCG Soto, MAFV Gonçalves - Molecular Therapy, 2024 - cell.com
The repurposing of RNA-programmable CRISPR systems from genome editing into
epigenome editing tools is gaining pace, including in research and development efforts …

Designing Epigenome Editors: Considerations of Biochemical and Locus Specificities

ZB Yagci, GR Kelkar, TJ Johnson, D Sen… - … Editing: Methods and …, 2024 - Springer
The advent of locus-specific protein recruitment technologies has enabled a new class of
studies in chromatin biology. Epigenome editors (EEs) enable biochemical modifications of …

The Reprimo gene family member, reprimo-like (rprml), is required for blood development in embryonic zebrafish

K Stanic, G Reig, RJ Figueroa, PA Retamal… - Scientific Reports, 2019 - nature.com
The Reprimo gene family comprises a group of single-exon genes for which their
physiological function remains poorly understood. Heretofore, mammalian Reprimo (RPRM) …

Designing epigenome editors: considerations of biochemical and locus specificities

D Sen, AJ Keung - Epigenome Editing: Methods and Protocols, 2018 - Springer
The advent of locus-specific protein recruitment technologies has enabled a new class of
studies in chromatin biology. Epigenome editors enable biochemical modifications of …

Design, Construction, and Validation of Targeted Gene Activation with TREE System in Human Cells

A Kunii, T Yamamoto, T Sakuma - Epigenomics: Methods and Protocols, 2022 - Springer
Genome editing technologies can be diverted into artificial transcription activators. In
particular, researchers have improved dCas9-based technologies by tandem-fusing or trans …

[PDF][PDF] the Reprimo gene family member, reprimo-like (rprml), is required for blood development in embryonic zebrafish

AH Corvalán, ML Concha, JD Amigo - researchgate.net
Karen stanic1, German Reig2, 8, Ignacio A. Wichmann3, 4, Juan C. opazo 5, Gareth I.
owen1, 3, 6, Alejandro H. Corvalán3, 4, Miguel L. Concha2, 7 & Julio D. Amigo1 the …

[引用][C] the Reprimo gene family member, reprimo-like (rprml), is required for blood development in embryonic zebrafish