The SLC2 genes code for a family of GLUT proteins that are part of the major facilitator
superfamily (MFS) of membrane transporters. Crystal structures have recently revealed how …

Metabolic syndrome (MetS) is a constellation of cardiometabolic risk factors, which together
predict increased risk of more serious chronic diseases. We propose that one consequence …

The structure and function of glucose transporters of the mammalian GLUT family of proteins
has been studied over many decades, and the proteins have fascinated numerous research …

In recent studies, the void of evaluation and in-depth understanding of unknown clinically
relevant potential molecular biomarkers involved in colorectal cancer (CRC) from the …

Recent research studies have shown that vitamin C (ascorbic acid) may affect bone mineral
density and that a deficiency of ascorbic acid leads to the development of osteoporosis …

Psoriasis is characterized by hyperproliferation and defective differentiation of keratinocytes
(KCs). Patients with psoriasis are at a high risk of developing diabetes and cardiovascular …

Introduction: Bronchopulmonary dysplasia (BPD) is a life-threatening lung illness that affects
premature infants and has a high incidence and mortality. Using interpretable machine …

Simple Summary Pain is experienced by~ 55% of patients who undergo anti-cancer
treatment. However, many genetic factors that are involved in the efficacy of opioid …

Hypoxia-inducible factor 1α is a key regulator of the hypoxia response in normal and cancer
tissues. It is well recognized to regulate glycolysis and is a target for therapy. However, how …

Purposes This study was conducted to identify the frequent mutations from reported Chinese
Gitelman syndrome (GS) patients, to predict the three-dimensional structure change of …