Bile acids are increasingly appearing in the spotlight owing to their novel impacts on various
host processes. Similarly, there is growing attention on members of the microbiota that are …

Bile acids are steroids generated at the interface of host and intestinal microbiota. While
primary bile acids are generated in the liver from cholesterol metabolism, secondary bile …

Bile acids regulate nutrient absorption and mitochondrial function, they establish and
maintain gut microbial community composition and mediate inflammation, and they serve as …

Lactic acid bacteria (LAB) plays a crucial role in the establishment and maintenance of host
health, as well as the improvement of some diseases. One of the major modes is the …

The repertoire of modifications to bile acids and related steroidal lipids by host and microbial
metabolism remains incompletely characterized. To address this knowledge gap, we …

Primary sclerosing cholangitis (PSC) is a rare, chronic liver disease with no approved
therapies. The ursodeoxycholic acid (UDCA) has been widely used, although there is no …

Cancer universally represents one of the largest public health concerns, substantially
contributing to global disease burden and mortality. The multifaceted interplay of …

Intestinal inflammation is a key determinant of intestinal and systemic health, and when our
intestines are damaged, there is disruption of the intestinal barrier, which in turn induces a …

Background Curcumin has been reported to have activity for prevention and therapy of CRC,
yet its underlying mechanisms remain largely unknown. Recently, emerging evidence …

This systematic literature review and meta‐analysis provide an overview of the critical role of
gut microbiota in modulating the efficacy of immunotherapy for colorectal cancer. Gut …