Organoids, miniature and simplified in vitro model systems that mimic the structure and
function of organs, have attracted considerable interest due to their promising applications in …

Machine learning is a subfield of artificial intelligence. The quality and versatility of machine
learning have been rapidly improving and playing a critical role in many aspects of social …

Background Single-cell RNA sequencing (scRNA-seq) measurements of gene expression
show great promise for studying the cellular heterogeneity of rice roots. How precisely …

The cardiac conduction system (CCS) is a network of specialized cardiomyocytes that
coordinates electrical impulse generation and propagation for synchronized heart …

Thyroid cancer, a prevalent form of endocrine malignancy, has witnessed a substantial
increase in occurrence in recent decades. To gain a comprehensive understanding of …

Motivation Automatic cell type annotation methods assign cell type labels to new datasets by
extracting relationships from a reference RNA-seq dataset. However, due to the limited …

Abstract Characterization of cell heterogeneity in gene expression is a “hot” but complex
issue in the fields of biology and medicine. Therefore, high-resolution RNA sequencing …

Single-cell RNA-seq (scRNA-seq) is a powerful technique for decoding the complex cellular
compositions in the tumor microenvironment (TME). As previous studies have defined many …

Summary Type 1 diabetes (T1D) is a chronic condition in which beta cells are destroyed by
immune cells. Despite progress in immunotherapies that could delay T1D onset, early …

Simple Summary Cancer is a complex disease that develops over time through accumulated
mutations in DNA that transform normal cells into a cancerous state. To fully capture the …