Osteomyelitis remains one of the greatest risks in orthopaedic surgery. Although many
organisms are linked to skeletal infections, Staphylococcus aureus remains the most …

Medical device-associated infections account for a large proportion of hospital-acquired
infections. A variety of opportunistic pathogens can cause implant infections, depending on …

Osteomyelitis is a devastating disease caused by microbial infection of bone. While the
frequency of infection following elective orthopedic surgery is low, rates of reinfection are …

The widespread use of biomaterials to support or replace body parts is increasingly
threatened by the risk of implant‐associated infections. In the quest for finding novel anti …

Titanium and its alloys have emerged as excellent candidates for use as orthopedic
biomaterials. Nevertheless, there are often complications arising after implantation of …

Infection of bone defects is a common clinical problem that negatively impacts bone repair
and may result in the development of antibiotic resistance due to the long-term use of …

Musculoskeletal infections (MSKI) remain the bane of orthopedic surgery, and result in
grievous illness and inordinate costs that threaten healthcare systems. As prevention …

Chronic implant-related bone infections are a major problem in orthopedic and trauma-
related surgery with severe consequences for the affected patients. As antibiotic resistance …

Staphylococcus aureus is a highly successful Gram-positive pathogen capable of causing
both superficial and invasive, life-threatening diseases. Of the invasive disease …

In the competition between the pathogen infection and the host defense, infectious
microorganisms may enter the host cells by evading host defense mechanisms and use the …