Chemical constituents and medicinal properties of Allium species

SMA Bastaki, S Ojha, H Kalasz, E Adeghate - Molecular and cellular …, 2021 - Springer
Allium species, belonging to Alliaceae family, are among the oldest cultivated vegetables
used as food. Garlic, onions, leeks and chives, which belong to this family, have been …

Potential therapeutic effects of functionally active compounds isolated from garlic

HM Yun, JO Ban, KR Park, CK Lee, HS Jeong… - Pharmacology & …, 2014 - Elsevier
The medicinal properties of functionally active organosulfur compounds such as allin, diallyl
disulfide, S-allylmercaptocysteine, and S-trityl-l-cysteine isolated from garlic have received …

Cellular mechanisms underlying the cardioprotective role of allicin on cardiovascular diseases

JL Sánchez-Gloria, AS Arellano-Buendía… - International journal of …, 2022 - mdpi.com
Cardiovascular diseases (CVDs) are a group of diseases in which the common denominator
is the affection of blood vessels, heart tissue, and heart rhythm. The genesis of CVD is …

[HTML][HTML] The ethnobotanical, bioactive compounds, pharmacological activities and toxicological evaluation of garlic (Allium sativum): A review

BC Okoro, TM Dokunmu, E Okafor, IA Sokoya… - Pharmacological …, 2023 - Elsevier
Abstract Background Garlic (Allium sativum) is a medicinal plant exploited for its diverse
pharmacological benefits and used as a cooking spice globally. In traditional Chinese …

[HTML][HTML] Allicin: A review of its important pharmacological activities

VD Savairam, NA Patil, SR Borate, MM Ghaisas… - Pharmacological …, 2023 - Elsevier
Abstract Background Garlic (Allium sativum L.) is known for its synthesis of allicin, a defense
molecule that exhibits various biological activities. Traditional medicine has utilized garlic to …

Antidiabetic effect of garlic

ASM Saikat, R Hossain, FB Mina, S Das… - Revista Brasileira de …, 2021 - Springer
Diabetes affects a substantial part of the world's population and, possibly, is the world's
fastest-growing metabolic disease. Garlic, Allium sativum L., Liliaceae, a popular cooking …

[HTML][HTML] Antihypertensive effect of allicin in dexamethasone-induced hypertensive rats

H Dubey, A Singh, AM Patole, CR Tenpe - Integrative medicine research, 2017 - Elsevier
Background Glucocorticoid is among the most commonly prescribed medicine.
Unfortunately, Excess glucocorticoid level leads hypertension in 80–90% patients. Garlic …

Allicin modulates diclofenac sodium induced hepatonephro toxicity in rats via reducing oxidative stress and caspase 3 protein expression

SH Orabi, D Abd Eldaium, A Hassan… - Environmental …, 2020 - Elsevier
Purpose This study was designed to evaluate the protective effects of allicin against
diclofenac sodium induced hepatonephro toxicity in rats. Methods Sixty male Wister albino …

Antidiabetic lead compounds and targets for drug development

GD Tupas, MCB Otero, IE Ebhohimen… - Phytochemicals as Lead …, 2020 - Elsevier
This chapter discusses the currently used and potential molecular targets of antidiabetic
agents. It includes the identification of prospective phytochemical lead compounds targeting …

Kinetics of modulatory role of Cyperus esculentus L. on the specific activity of key carbohydrate metabolizing enzymes

S Sabiu, EO Ajani, TO Sunmonu, AOT Ashafa - African Journal of …, 2017 - ajol.info
Background: The continuous search for new lead compounds as viable inhibitors of specific
enzymes linked to carbohydrate metabolism has intensified. Cyperus esculentus L. is one of …