Oxytocin, erectile function and sexual behavior: last discoveries and possible advances

MR Melis, A Argiolas - International journal of molecular sciences, 2021 - mdpi.com
A continuously increasing amount of research shows that oxytocin is involved in numerous
central functions. Among the functions in which oxytocin is thought to be involved are those …

Biased oxytocinergic modulation of midbrain dopamine systems

L Xiao, MF Priest, J Nasenbeny, T Lu, Y Kozorovitskiy - Neuron, 2017 - cell.com
The release of dopamine (DA) regulates rewarding behavior and motor actions through
striatum-targeting efferents from ventral tegmental area (VTA) and substantia nigra pars …

Oxytocin as an Anti-obesity Treatment

JJ Niu, J Tong, JE Blevins - Frontiers in neuroscience, 2021 - frontiersin.org
Obesity is a growing health concern, as it increases risk for heart disease, hypertension, type
2 diabetes, cancer, COVID-19 related hospitalizations and mortality. However, current …

Oxytocin attenuates phencyclidine hyperactivity and increases social interaction and nucleus accumben dopamine release in rats

S Kohli, MV King, S Williams, A Edwards… - …, 2019 - nature.com
The pituitary neuropeptide oxytocin promotes social behavior, and is a potential adjunct
therapy for social deficits in schizophrenia and autism. Oxytocin may mediate pro-social …

Effect of sex and autism spectrum disorder on oxytocin receptor binding and mRNA expression in the dopaminergic pars compacta of the human substantia nigra

SS Frehner, KT Dooley… - … of the Royal …, 2022 - royalsocietypublishing.org
Oxytocin is an endogenous neuropeptide hormone that influences social behaviour and
bonding in mammals. Variations in oxytocin receptor (OXTR) expression may play a role in …

Role of oxytocin in the ventral tegmental area in social reinforcement

JM Borland, KN Grantham, LM Aiani, KJ Frantz… - …, 2018 - Elsevier
The rewarding properties of social interactions play a critical role in the development and
maintenance of social relationships, and deficits in social reward are associated with various …

[HTML][HTML] Molecular, biochemical and behavioural evidence for a novel oxytocin receptor and serotonin 2C receptor heterocomplex

B Chruścicka, CSM Cowan, SEW Fitzsimons… - …, 2021 - Elsevier
The complexity of oxytocin-mediated functions is strongly associated with its modulatory
effects on other neurotransmission systems, including the serotonin (5-hydroxytryptamine, 5 …

NTS and VTA oxytocin reduces food motivation and food seeking

HS Wald, A Chandra, A Kalluri… - American Journal …, 2020 - journals.physiology.org
Oxytocin (OT) is a neuropeptide whose central receptor-mediated actions include reducing
food intake. One mechanism of its behavioral action is the amplification of the feeding …

Heteromerization of dopamine D2 and oxytocin receptor in adult striatal astrocytes

S Amato, M Averna, D Guidolin, C Ceccoli… - International Journal of …, 2023 - mdpi.com
The ability of oxytocin (OT) to interact with the dopaminergic system through facilitatory D2-
OT receptor (OTR) receptor-receptor interaction in the limbic system is increasingly …

Missing pieces in decoding the brain oxytocin puzzle: Functional insights from mouse brain wiring diagrams

SB Manjila, R Betty, Y Kim - Frontiers in Neuroscience, 2022 - frontiersin.org
The hypothalamic neuropeptide, oxytocin (Oxt), has been the focus of research for decades
due to its effects on body physiology, neural circuits, and various behaviors. Oxt elicits a …