The discovery of aquaporin water channels by Agre and coworkers answered a long-
standing biophysical question of how the majority of water crosses biological membranes …

A number of ion channels and transporters are expressed in both the inner ear and kidney.
In the inner ear, K+ cycling and endolymphatic K+, Na+, Ca2+, and pH homeostasis are …

The aquaporins (AQPs) are a family of small integral membrane proteins that facilitate the
bidirectional transport of water across biological membranes in response to osmotic …

Orthogonal arrays or assemblies of intramembranous particles (OAPs) are structures in the
membrane of diverse cells which were initially discovered by means of the freeze-fracturing …

ITPs has impacted otology and neurotology practice due to increased utilization. A sound
understanding of the basic science and clinical studies is needed to establish long-term …

Hearing impairments are the most common symptom of congenital defects, and they
generally remain intractable to treatment. Pendred syndrome, the most frequent syndromic …

Aquaporins (AQPs) are membrane proteins serving in the transfer of water and small solutes
across cellular membranes. AQPs play a variety of roles in the body such as urine formation …

The lack of cochlear regenerative potential is the main cause for the permanence of hearing
loss. Albeit quiescent in vivo, dissociated non-sensory cells from the neonatal cochlea …

Meniere's disease is a poorly understood, disabling syndrome causing spells of vertigo,
hearing fluctuation, tinnitus, and aural fullness. In this paper, we present a review of the …

Age-related hearing loss (presbyacusis) is the most common type of hearing impairment.
One of the most consistent pathological changes seen in presbyacusis is the loss of spiral …