Calpains are a family of proteases that were scientifically recognized earlier than
proteasomes and caspases, but remain enigmatic. However, they are known to participate in …

STING (stimulator of interferon genes) has recently been found to play an important role in
host defenses against virus and intracellular bacteria via the regulation of type-I IFN …

Metastatic dissemination represents the final stage of tumor progression as well as the
principal cause of cancer‐associated deaths. Calpains are a conserved family of calcium …

Increasing evidence indicates that long noncoding RNA SPRY4 intronic transcript 1 (lncRNA
SPRY4-IT1) has been reported to be associated with the progression of several cancers, but …

Metastasis remains a crucial obstacle to the clinical treatment of hepatocellular carcinoma
(HCC). Investigating the potential anti-tumor compounds from medicinal herb against HCC …

Nectins are Ca2+‑independent immunoglobulin‑like cell adhesion molecules that belong to
a family of four members that function in a number of biological cellular activities. Nectin‑4 is …

Nectin-4, a member of the Nectin family that includes 4 Ca+-independent immunoglobulin-
like cell adhesion molecules, plays a carcinogenic role in multiple cancers. However, Nectin …

ABSTRACT Introduction: Calpains are intracellular Ca2+-dependent cysteine proteases with
15 known members in the enzyme family. They act as regulatory enzymes, their cleavage …

Background Aberrant expression of microRNAs (miRNAs) contributes to the development of
high grade serous ovarian cancer (HGSOC). However, the molecular mechanism by which …

Spinocerebellar ataxia type 3 (SCA3) is a hereditary ataxia caused by inheritance of a
mutated form of the human ATXN3 gene containing an expanded CAG repeat region …