[HTML][HTML] Polymer-and lipid-based nanocarriers for ocular drug delivery: current status and future perspectives

H Han, S Li, M Xu, Y Zhong, W Fan, J Xu, T Zhou… - Advanced Drug Delivery …, 2023 - Elsevier
Ocular diseases seriously affect patients' vision and life quality, with a global morbidity of
over 43 million blindness. However, efficient drug delivery to treat ocular diseases …

[HTML][HTML] Nanotechnology based drug delivery systems for the treatment of anterior segment eye diseases

AL Onugwu, CS Nwagwu, OS Onugwu… - Journal of Controlled …, 2023 - Elsevier
Diseases affecting the anterior segment of the eye are the primary causes of vision
impairment and blindness globally. Drug administration through the topical ocular route is …

Ocular drug delivery: a comprehensive review

S Ahmed, MM Amin, S Sayed - AAPS PharmSciTech, 2023 - Springer
The human eye is a sophisticated organ with distinctive anatomy and physiology that
hinders the passage of drugs into targeted ophthalmic sites. Effective topical administration …

Ocular drug delivery: present innovations and future challenges

V Gote, S Sikder, J Sicotte, D Pal - Journal of Pharmacology and …, 2019 - ASPET
Ocular drug delivery has always been a challenge for ophthalmologists and drug-delivery
scientists due to the presence of various anatomic and physiologic barriers. Inimitable static …

Lipid nanoparticles as a promising drug delivery carrier for topical ocular therapy—an overview on recent advances

S Jacob, AB Nair, J Shah, S Gupta, SHS Boddu… - Pharmaceutics, 2022 - mdpi.com
Due to complicated anatomical and physical properties, targeted drug delivery to ocular
tissues continues to be a key challenge for formulation scientists. Various attempts are …

Hyaluronic acid in ocular drug delivery

X Zhang, D Wei, Y Xu, Q Zhu - Carbohydrate Polymers, 2021 - Elsevier
As a naturally-occurring polysaccharide which could be found in various ophthalmic tissues,
hyaluronic acid (HA) has a wide range of applications in the eye, including treatment of dry …

Pharmaceutical nanocrystals: production by wet milling and applications

M Malamatari, KMG Taylor, S Malamataris… - Drug Discovery …, 2018 - Elsevier
Highlights•Nanocrystals are nanosized drug particles produced in the form of
nanosuspensions.•Nanocrystals are an industrially feasible formulation for poorly soluble …

Emerging nano-formulations and nanomedicines applications for ocular drug delivery

D Khiev, ZA Mohamed, R Vichare, R Paulson, S Bhatia… - Nanomaterials, 2021 - mdpi.com
Ocular diseases can deteriorate vision to the point of blindness and thus can have a major
impact on the daily life of an individual. Conventional therapies are unable to provide …

Ocular drug delivery: Role of degradable polymeric nanocarriers for ophthalmic application

CH Tsai, PY Wang, IC Lin, H Huang, GS Liu… - International journal of …, 2018 - mdpi.com
Ocular drug delivery has been a major challenge for clinical pharmacologists and
biomaterial scientists due to intricate and unique anatomical and physiological barriers in …

A comprehensive review on contact lens for ophthalmic drug delivery

J Xu, Y Xue, G Hu, T Lin, J Gou, T Yin, H He… - Journal of controlled …, 2018 - Elsevier
With the prevalence of electronic devices and an aging population, the number of people
affected with eye disease is increasing year by year. In spite of a large number of eye drops …