Methylglyoxal (MG) is a potent protein glycating agent. Glycation is directed to guanidino
groups of arginine residues forming mainly hydroimidazolone N δ-(5-hydro-5-methyl-4 …

Diabetes is one of the most frequent diseases throughout the world and its incidence is
predicted to exponentially progress in the future. This metabolic disorder is associated with …

The reactive dicarbonyl metabolite methylglyoxal (MG) is the precursor of the major
quantitative advanced glycation endproducts (AGEs) in physiological systems-arginine …

The effect of pH on the conformational behavior of Candida antartica lipase B (CaLB) has
been monitored by spectroscopic and calorimetric studies. The results obtained from far and …

This is an introduction to a collection of review articles by leading investigators in the field of
protein glycation research, see following articles in this issue. With this we launch a section …

The proteins of the human eye are highly susceptible to the formation of advanced glycation
end products (AGEs) from the reaction of sugars and carbonyl compounds. AGEs …

Significance: Obesity and type 2 diabetes mellitus are increasing globally. There is also
increasing associated complications, such as non-alcoholic fatty liver disease (NAFLD) and …

Protein glycation in biological systems occurs predominantly on lysine, arginine and N-
terminal residues of proteins. Major quantitative glycation adducts are found at mean extents …

The present study deals with the mechanistic reaction pathway of the α-dicarbonyl
compound methylglyoxal with the guanidino group of arginine. Eight products were formed …

The methylglyoxal-derived hydroimidazolones (MG-Hs) comprise the most prevalent class of
non-enzymatic, post-translational modifications of protein arginine residues found in nature …