Evolving role of calcium density in coronary artery calcium scoring and atherosclerotic cardiovascular disease risk

AC Razavi, AS Agatston, LJ Shaw, CN De Cecco… - Cardiovascular …, 2022 - jacc.org
Coronary artery calcium (CAC) is a specific marker of coronary atherosclerosis that can be
used to measure calcified subclinical atherosclerotic burden. The Agatston method is the …

Assessment of Subclinical Atherosclerosis in Asymptomatic People In Vivo: Measurements Suitable for Biomarker and Mendelian Randomization Studies

PK Garg, HS Bhatia, TS Allen, T Grainger… - … and Vascular Biology, 2024 - Am Heart Assoc
BACKGROUND: One strategy to reduce the burden of cardiovascular disease is the early
detection and treatment of atherosclerosis. This has led to significant interest in studies of …

New Cardiovascular Risk Assessment Techniques for Primary Prevention: JACC Review Topic of the Week

KP Verma, M Inouye, PJ Meikle, SJ Nicholls… - Journal of the American …, 2022 - jacc.org
Risk factor–based models fail to accurately estimate risk in select populations, in particular
younger individuals. A sizable number of people are also classified as being at intermediate …

Discordance between coronary artery calcium area and density predicts long-term atherosclerotic cardiovascular disease risk

AC Razavi, M van Assen, CN De Cecco… - Cardiovascular …, 2022 - jacc.org
Background Coronary artery calcium (CAC) is commonly quantified as the product of 2
generally correlated measures: plaque area and calcium density. Objectives The authors …

Lipoprotein (a) and coronary artery calcium in comparison with other lipid biomarkers: the multi-ethnic study of atherosclerosis

CL Jackson, PK Garg, W Guan, MY Tsai… - Journal of Clinical …, 2023 - Elsevier
Background Coronary artery calcium (CAC) scoring is often used for atherosclerotic
cardiovascular disease (ASCVD) risk stratification in individuals with elevated lipoprotein …

Coronary artery calcium density and cardiovascular events by volume level: the MESA

HS Bhatia, RL McClelland, J Denenberg… - Circulation …, 2023 - Am Heart Assoc
Background: The Agatston coronary artery calcium (CAC) score provides robust
cardiovascular disease risk prediction but upweights plaque area by a density factor …

Coronary artery calcium incidence and changes using direct plaque measurements: the MASALA study

HS Bhatia, F Lin, IC Thomas, J Denenberg… - Atherosclerosis, 2022 - Elsevier
Background and aims We aimed to identify predictors of change in direct measures of
coronary artery calcium (CAC) volume and density in South Asian participants. Methods We …

Coronary artery calcium dispersion and cause-specific mortality

R Dudum, ZA Dardari, DI Feldman, DS Berman… - The American journal of …, 2023 - Elsevier
Coronary artery calcium (CAC) measures subclinical atherosclerosis and improves risk
stratification. CAC characteristics—including vessel (s) involved, number of vessels, volume …

Great debate: lipid-lowering therapies should be guided by vascular imaging rather than by circulating biomarkers

L Tokgozoglu, DA Morrow, SJ Nicholls - European heart journal, 2023 - academic.oup.com
Dyslipidemia is an important modifiable risk factor for atherosclerotic cardiovascular disease
(ASCVD) and lipid lowering an integral component of cardiovascular prevention …

Relationship between the triglyceride–glucose index and coronary artery calcification in asymptomatic, non-diabetic patients undergoing maintenance hemodialysis

H Ding, J Zhu, Y Tian, L Xu, L Song, Y Shi, D Mu… - Renal …, 2023 - Taylor & Francis
Objective Coronary artery calcification (CAC) is positively and independently associated
with cardiovascular disease (CVD) in patients undergoing maintenance hemodialysis …