Single-molecule fluorescence techniques are ideally suited to provide information about the
structure-function-dynamics relationship of a biomolecule as static and dynamic …

Water-soluble organic fluorophores are widely used as labels in biological systems.
However, in many cases these fluorophores can interact strongly with lipid bilayers …

Molecular recognition reagents are key tools for understanding biological processes and are
used universally by scientists to study protein expression, localisation and interactions …

Probe choice in single-molecule microscopy requires deeper evaluations than those
adopted for less sensitive fluorescence microscopy studies. Indeed, fluorophore …

Single-molecule techniques are powerful tools to investigate the structure and dynamics of
macromolecular complexes; however, data quality can suffer because of weak specific …

Single-molecule imaging is invaluable for investigating the heterogeneous behavior and
interactions of biological molecules. However, an impediment to precise sampling of single …

Super-resolution fluorescence microscopy plays a crucial role in our understanding of cell
structure and function by reporting cellular ultrastructure with 20–30 nm resolution. However …

Kidney transplant recipients (KTRs) are at increased risk for a more severe course of COVID-
19, due to their pre-existing comorbidity and immunosuppression. Consensus protocols …

Zero mode waveguide (ZMW) nanoapertures efficiently confine the light down to the
nanometer scale and overcome the diffraction limit in single molecule fluorescence analysis …

Three-dimensional nanoscale cross-link density variations are an important and
incompletely understood morphological aspect of polymer gels. Here, within the context of …