Here, we highlight the potential translational benefits of delivering FLASH radiotherapy
using ultra-high dose rates (> 100 Gy⋅ s− 1). Compared with conventional dose-rate …

Cranial irradiation for the treatment of brain cancer elicits progressive and severe cognitive
dysfunction that is associated with significant neuropathology. Radiation injury in the CNS …

Radiation therapy, a common treatment for central nervous system cancers, can negatively
impact cognitive function, resulting in radiation-induced cognitive decline (RICD). RICD …

Wharton's jelly mesenchymal stem cells (WJ-MSCs) are gaining significant attention in
regenerative medicine for their potential to treat degenerative diseases and mitigate …

Background Regenerative therapies to mitigate Alzheimer's disease (AD) neuropathology
have shown very limited success. In the recent era, extracellular vesicles (EVs) derived from …

Objective Studies have shown that the therapeutic effects of mesenchymal stem cells
(MSCs) are mediated in a paracrine manner, mainly through extracellular vesicles such as …

Cancer survivors face a variety of challenges as they cope with disease recurrence and a
myriad of normal tissue complications brought on by radio-and chemotherapeutic treatment …

Cranial radiotherapy, although beneficial for the treatment of brain tumors, inevitably leads
to normal tissue damage that can induce unintended neurocognitive complications that are …

Numerous clinical studies have established the debilitating neurocognitive side effects of
chemotherapy in the treatment of breast cancer, often referred as chemobrain. We …

Based on the most recent estimates by the Canadian Cancer Society, 2 in 5 Canadians will
develop cancer in their lifetimes. More than half of all cancer patients receive some type of …