Zebrafish have several advantages compared to other vertebrate models used in modeling
human diseases, particularly for large-scale genetic mutant and therapeutic compound …

Over the past two decades, super-resolution microscopy (SRM), which offered a significant
improvement in resolution over conventional light microscopy, has become a powerful tool …

The automobile tire antioxidant N-(1, 3-dimethylbutyl)-N'-phenyl-p-phenylenediamine
(6PPD) and its quinone metabolite 6PPDQ have recently received much attention for their …

Paracrine Wnt/β-catenin signalling is important during developmental processes, tissue
regeneration and stem cell regulation. Wnt proteins are morphogens, which form …

Tissue regeneration is a crucial self-renewal capability involving many complex biological
processes. Although transgenic techniques and fluorescence immunohistochemical staining …

Microglia are brain resident macrophages important for brain development, connectivity,
homeostasis and disease. However, it is still largely unclear how microglia functions and …

Embryonic and larval Danio rerio (zebrafish) is increasingly used as a toxicological model to
conduct rapid in vivo tests and developmental toxicity assays; the zebrafish features high …

Rare diseases are collectively common and often extremely debilitating. Following the
emergence of next-generation sequencing (NGS) technologies, the variants underpinning …

Preclinical screening with animal models is an important initial step in clinical translation of
new drug delivery systems. However, establishing efficacy, biodistribution, and biotoxicity of …

Due to the negative consequences associated with the use of antibiotics, researchers, and
food producers have studied alternatives, such as probiotics, for the control of fish diseases …