Heart failure (HF) is an acute or chronic clinical syndrome that results in a decrease in
cardiac output and an increase in intracardiac pressure at rest or upon exertion. The …

Obstructive sleep apnea is an underdiagnosed sleep-related breathing disorder affecting
millions of people. Recurrent episodes of apnea/hypopnea result in intermittent hypoxia …

Injectable hydrogels have significant therapeutic potential for treatment of myocardial
infarction (MI) through tissue bulking and local drug delivery, including the delivery of small …

The aim of the present study was to investigate the effect of morroniside against matrix
metalloproteinase (MMP) 2/9 and focal cerebral ischemia/reperfusion (I/R) injury in rats. A …

Myocardial ischemia-reperfusion injury (MIRI) is an important factor leading to myocardial
injury and necrosis, and can induce ischemic heart disease. Forkhead box protein N4 …

Our aim in this study was to evaluate the effect of physical training performed before CABG
on the perioperative dynamics of the serum levels of asymmetric dimethylarginine (ADMA) …

Restoration of blood flow to myocardium previously subjected to ischemia leads to
ischemia/reperfusion injury due to oxidative stress. An increased production of toxic …

1. ABSTRACT Matrix metalloproteinase-2(MMP-2) mediated degradation of myosin light
chain 1 (MLC1) and troponin I (TnI) contributes to myocardial ischemia/reperfusion (I/R) …

Injury of myocardium during ischaemia/reperfusion (I/R) is a complex and multifactorial
process involving uncontrolled protein phosphorylation, nitration/nitrosylation by increased …

Ischemia/reperfusion (I/R) injury is accompanied by an increase of matrix metalloproteinase
2 (MMP‐2) activity, which degrades heart contractile proteins. The aim of the study was to …