Radioprotection and radiomitigation: from the bench to clinical practice

E Obrador, R Salvador, JI Villaescusa, JM Soriano… - Biomedicines, 2020 - mdpi.com
The development of protective agents against harmful radiations has been a subject of
investigation for decades. However, effective (ideal) radioprotectors and radiomitigators …

Chromatin and the cellular response to particle radiation-induced oxidative and clustered DNA damage

JM Danforth, L Provencher… - Frontiers in Cell and …, 2022 - frontiersin.org
Exposure to environmental ionizing radiation is prevalent, with greatest lifetime doses
typically from high Linear Energy Transfer (high-LET) alpha particles via the radioactive …

Integrating evolutionarily conserved mechanism of response to radiation for exploring novel Caenorhabditis elegans radiation-responsive genes for estimation of …

L Zhao, Z Li, B Huang, D Mi, D Xu, Y Sun - Chemosphere, 2024 - Elsevier
During space exploration, space radiation is widely recognized as an inescapable perilous
stressor, owing to its capacity to induce genomic DNA damage and escalate the likelihood of …

Comparative metabolic profiles of total and partial body radiation exposure in mice using an untargeted metabolomics approach

K Maan, R Tyagi, A Dutta, R Bakhshi, P Rana - Metabolomics, 2020 - Springer
Introduction A large scale population exposure to ionizing radiation during intentional or
unintentional nuclear accidents undoubtedly generates a complex scenario with partial …

British nuclear test veteran family trios for the study of genetic risk

C Rake, C Gilham, M Scholze, L Bukasa… - Journal of …, 2022 - iopscience.iop.org
The risk of radiation effects in children of individuals exposed to ionising radiation remains
an ongoing concern for aged veterans of the British nuclear testing programme. The genetic …

Evaluation of micronuclei and antioxidant status in hospital radiation workers occupationally exposed to low-dose ionizing radiation

SN Mousavikia, MT Bahreyni Toossi… - BMC Health Services …, 2023 - Springer
Purpose There is scientific evidence that ionizing radiation (IR) can be responsible for
various health hazards that are one of the concerns in occupational exposure. This study …

[HTML][HTML] Dose estimation after a mixed field exposure: Radium-223 and intensity modulated radiotherapy

I Bastiani, SJ McMahon, P Turner, KM Redmond… - Nuclear Medicine and …, 2022 - Elsevier
Abstract Introduction Radium-223 dichloride ([223 Ra] RaCl 2), a radiopharmaceutical that
delivers α-particles to regions of bone metastatic disease, has been proven to improve …

Biological dosimetry dose-response curves for residents living near nuclear power plants in South Korea

SK Jeong, SJ Oh, YR Kang, HJ Kim, YU Kye… - Science …, 2023 - journals.sagepub.com
The purpose of this study was to establish the dose–response curves for biological
dosimetry of the Dong Nam Institute of Radiological and Medical Sciences to monitor …

A multi-detector experimental setup for the study of space radiation shielding materials: Measurement of secondary radiation behind thick shielding and assessment of …

F Horst, D Boscolo, G Cartechini… - EPJ Web of …, 2022 - epj-conferences.org
Space agencies have recognized the risks of astronauts' exposure to space radiation and
are developing complex model-based risk mitigation strategies. In the foundation of these …

Genetic and environmental associations of nonspecific chromosomal aberrations

K Hemminki, Y Niazi, L Vodickova, P Vodicka… - Mutagenesis, 2024 - academic.oup.com
Nonspecific structural chromosomal aberrations (CAs) are found in around 1% of circulating
lymphocytes from healthy individuals but the frequency may be higher after exposure to …