Abstract The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic
Shock 2020 (J-SSCG 2020), a Japanese-specific set of clinical practice guidelines for sepsis …

Background: This document provides evidence-based clinical practice guidelines on the
management of adult patients with community-acquired pneumonia. Methods: A …

Community-acquired pneumonia is not usually considered a high-priority problem by the
public, although it is responsible for substantial mortality, with a third of patients dying within …

Background Empiric antibiotics for community acquired bacterial pneumonia (CABP) are
often prescribed to patients with COVID-19, despite a low reported incidence of co …

Antibiotic de-escalation is an appealing strategy in antibiotic stewardship programmes. We
aimed to assess its safety and effects using a systematic review and meta-analysis. We …

Die vorliegende Leitlinie umfasst ein aktualisiertes Konzept der Behandlung und Prävention
von erwachsenen Patienten mit ambulant erworbener Pneumonie und löst die bisherige …

Pneumonia is a leading cause of hospitalization and death due to infection worldwide.
Streptococcus pneumoniae and Legionella pneumophila remain among the most commonly …

Background De-escalation therapy is a strategy used widely to treat infections while
avoiding the use of broad-spectrum antimicrobials. However, there is a paucity of clinical …

Background Although antibiotic de-escalation is regarded as a measure that reduces
selection pressure, adverse drug effects and costs, evidence supporting this practice in …

Introduction: Community-acquired pneumonia (CAP) continues to be associated with
significant mortality and morbidity. As with other infectious diseases, in recent years there …