Hypoxic-ischemic encephalopathy: a review for the clinician

M Douglas-Escobar, MD Weiss - JAMA pediatrics, 2015 - jamanetwork.com
Importance Hypoxic-ischemic encephalopathy (HIE) occurs in 1 to 8 per 1000 live births in
developed countries. Historically, the clinician has had little to offer neonates with HIE other …

Management of acute right ventricular failure in the intensive care unit

CE Ventetuolo, JR Klinger - Annals of the American Thoracic …, 2014 - atsjournals.org
Right ventricular (RV) failure occurs when the RV fails to maintain enough blood flow
through the pulmonary circulation to achieve adequate left ventricular filling. This can occur …

Double-blind prospective randomized controlled trial of dopamine versus epinephrine as first-line vasoactive drugs in pediatric septic shock

AMC Ventura, HH Shieh, A Bousso, PF Góes… - Critical care …, 2015 - journals.lww.com
Objectives: The primary outcome was to compare the effects of dopamine or epinephrine in
severe sepsis on 28-day mortality; secondary outcomes were the rate of healthcare …

Persistent pulmonary hypertension of the newborn: advances in diagnosis and treatment

A Jain, PJ McNamara - Seminars in Fetal and Neonatal Medicine, 2015 - Elsevier
Persistent pulmonary hypertension of the newborn (PPHN) is a frequent cause for admission
to the neonatal intensive care unit and is associated with mortality and variable morbidities …

Milrinone improves oxygenation in neonates with severe persistent pulmonary hypertension of the newborn

PJ McNamara, F Laique, S Muang-In, HE Whyte - Journal of critical care, 2006 - Elsevier
BACKGROUND: Many neonates with severe persistent pulmonary hypertension of the
newborn (PPHN) are nonresponders to inhaled nitric oxide (iNO). Milrinone is a promising …

Hemodynamic instability in the critically ill neonate: an approach to cardiovascular support based on disease pathophysiology

RE Giesinger, PJ McNamara - Seminars in perinatology, 2016 - Elsevier
Hemodynamic disturbance in the sick neonate is common, highly diverse in underlying
pathophysiology and dynamic. Dysregulated systemic and cerebral blood flow is …

Pulmonary hypertension and the asphyxiated newborn

A Lapointe, KJ Barrington - The Journal of pediatrics, 2011 - Elsevier
Persistent pulmonary hypertension of the newborn may occur with perinatal asphyxia, either
because of direct effects of hypoxia/ischemia on pulmonary arterial function or indirectly …

Management of multi organ dysfunction in neonatal encephalopathy

M O'Dea, D Sweetman, SL Bonifacio, M El-Dib… - Frontiers in …, 2020 - frontiersin.org
Neonatal Encephalopathy (NE) describes neonates with disturbed neurological function in
the first post-natal days of life. NE is an overall term that does not specify the etiology of the …

Vein of Galen aneurysmal malformation: rationalizing medical management of neonatal heart failure

MJ Cory, P Durand, R Sillero, L Morin, R Savani… - Pediatric …, 2023 - nature.com
Neonates who present in high output heart failure secondary to vein of Galen aneurysmal
malformation can be difficult to manage medically due to the complex physiology that results …

[HTML][HTML] Beyond the inhaled nitric oxide in persistent pulmonary hypertension of the newborn

MY Lai, SM Chu, S Lakshminrusimha, HC Lin - Pediatrics & Neonatology, 2018 - Elsevier
Persistent pulmonary hypertension (PPHN) is a consequence of failed pulmonary vascular
transition at birth and leads to pulmonary hypertension with shunting of deoxygenated blood …