[HTML][HTML] Photonic and magnetic materials for on-demand local drug delivery

I Armenia, CC Ayllón, BT Herrero, F Bussolari… - Advanced drug delivery …, 2022 - Elsevier
Nanomedicine has been considered a promising tool for biomedical research and clinical
practice in the 21st century because of the great impact nanomaterials could have on human …

[HTML][HTML] Nanomedicines: The magic bullets reaching their target?

B Flühmann, I Ntai, G Borchard, S Simoens… - European Journal of …, 2019 - Elsevier
Nanomedicines, since the approval of the first one in the 1950s, have been accompanied by
expectations of higher efficiency and efficacy, compared to less complex drugs. The …

Active ingredient vs excipient debate for nanomedicines

E Hemmrich, S McNeil - nature nanotechnology, 2023 - nature.com
Nanomedicines are complex drugs where components that have typically been regarded as
excipients may now be considered part of the active ingredient. The distinction between the …

A nanomedicine structure–activity framework for research, development, and regulation of future cancer therapies

B Youden, R Jiang, AJ Carrier, MR Servos, X Zhang - ACS nano, 2022 - ACS Publications
Despite their clinical success in drug delivery applications, the potential of theranostic
nanomedicines is hampered by mechanistic uncertainty and a lack of science-informed …

The consolidation of nanomedicine

R Zingg, M Fischer - Wiley Interdisciplinary Reviews …, 2019 - Wiley Online Library
Over the past two decades, nanomedicine has grown steadily, however, without inducing a
palpable shift in the diagnosis and treatment of diseases so far. While this may simply be a …

The Hitchhiker's guide to human therapeutic nanoparticle development

TI Ramos, CA Villacis-Aguirre, KV López-Aguilar… - Pharmaceutics, 2022 - mdpi.com
Nanomedicine plays an essential role in developing new therapies through novel drug
delivery systems, diagnostic and imaging systems, vaccine development, antibacterial tools …

An elucidative review to analytically sieve the viability of nanomedicine market

A Kad, A Pundir, SK Arya, N Bhardwaj… - Journal of Pharmaceutical …, 2020 - Springer
The advent of the twenty-first century marked a paradigm shift in the healthcare sector with
coming of automated, sensitive, targeted medicines and technologies having diagnostic …

Report of the AAPS guidance forum on the FDA draft guidance for industry:“Drug products, including biological products, that contain nanomaterials”

JSB de Vlieger, DJA Crommelin, K Tyner… - 2019 - Springer
To guide developers of innovative and generic drug products that contain nanomaterials, the
US Food and Drug Administration issued the draft guidance for industry titled:“Drug …

[HTML][HTML] Critical nanomaterial attributes of iron-carbohydrate nanoparticles: leveraging orthogonal methods to resolve the 3-dimensional structure

L Krupnik, P Joshi, A Kappler, B Flühmann… - European Journal of …, 2023 - Elsevier
Intravenous iron-carbohydrate nanomedicines are widely used to treat iron deficiency and
iron deficiency anemia across a wide breadth of patient populations. These colloidal …

Regulatory science approach in pharmaceutical development of follow-on versions of non-biological complex drug products

DM Zagalo, S Simões, J Sousa - Journal of Pharmaceutical Sciences, 2022 - Elsevier
Scientific and technological breakthroughs in the field of Nanotechnology have been a
driving force throughout the development and approval of Non-Biological Complex Drugs …