Ring opening polymerization of α-amino acids: advances in synthesis, architecture and applications of polypeptides and their hybrids
AR Mazo, S Allison-Logan, F Karimi… - Chemical society …, 2020 - pubs.rsc.org
Polypeptides have attracted considerable attention in recent decades due to their inherent
biodegradability and tunable cytocompatibility. Macromolecular design in conjunction with …
biodegradability and tunable cytocompatibility. Macromolecular design in conjunction with …
Recent Advances and Future Developments in the Preparation of Polypeptides via N-Carboxyanhydride (NCA) Ring-Opening Polymerization
Polypeptides have the same or similar backbone structures as proteins and peptides,
rendering them as suitable and important biomaterials. Amino acid N-carboxyanhydrides …
rendering them as suitable and important biomaterials. Amino acid N-carboxyanhydrides …
Intelligent poly (l-histidine)-based nanovehicles for controlled drug delivery
Stimuli-responsive drug delivery systems based on polymeric nanovehicles are among the
most promising treatment regimens for malignant cancers. Such intelligent systems that …
most promising treatment regimens for malignant cancers. Such intelligent systems that …
Recent Advances in Poly(α-L-glutamic acid)-Based Nanomaterials for Drug Delivery
Poly (α-L-glutamic acid)(PGA) is a class of synthetic polypeptides composed of the
monomeric unit α-L-glutamic acid. Owing to their biocompatibility, biodegradability, and non …
monomeric unit α-L-glutamic acid. Owing to their biocompatibility, biodegradability, and non …
A moisture-tolerant route to unprotected α/β-amino acid N-carboxyanhydrides and facile synthesis of hyperbranched polypeptides
A great hurdle in the production of synthetic polypeptides lies in the access of N-
carboxyanhydrides (NCA) monomers, which requires dry solvents, Schlenk line/gloveboxe …
carboxyanhydrides (NCA) monomers, which requires dry solvents, Schlenk line/gloveboxe …
Living/controlled anionic polymerization of glycolide in fluoroalcohols: toward sustainable bioplastics
Ring-opening polymerization (ROP) is a promising approach to accessing well-defined
polyesters with superior (bio) degradability and recyclability. However, the living/controlled …
polyesters with superior (bio) degradability and recyclability. However, the living/controlled …
A nanoscale MOF-based heterogeneous catalytic system for the polymerization of N-carboxyanhydrides enables direct routes toward both polypeptides and related …
Y Liu, Z Ren, N Zhang, X Yang, Q Wu, Z Cheng… - Nature …, 2023 - nature.com
Synthetic polypeptides have emerged as versatile tools in both materials science and
biomedical engineering due to their tunable properties and biodegradability. While the …
biomedical engineering due to their tunable properties and biodegradability. While the …
Precision Synthesis of Polypeptides via Living Anionic Ring-Opening Polymerization of N-Carboxyanhydrides by Tri-thiourea Catalysts
The chemistry of α-amino acid N-carboxyanhydrides (NCAs) has a history of over 100 years,
but precise and efficient ring-opening polymerization methods for NCAs remain highly …
but precise and efficient ring-opening polymerization methods for NCAs remain highly …
Degradable polymers via olefin metathesis polymerization
The development of degradable polymers has commanded significant attention over the
past half century. Approaches have predominantly relied on ring-opening polymerization of …
past half century. Approaches have predominantly relied on ring-opening polymerization of …
Superfast and Water‐Insensitive Polymerization on α‐Amino Acid N‐Carboxyanhydrides to Prepare Polypeptides Using Tetraalkylammonium Carboxylate as the …
We design the tetraalkylammonium carboxylate‐initiated superfast polymerization on α‐
amino acid N‐carboxyanhydrides (NCA) for efficient synthesis of polypeptides …
amino acid N‐carboxyanhydrides (NCA) for efficient synthesis of polypeptides …